Transcriptome Analysis Identifies Key Metabolic Changes in the Hooded Seal (Cystophora cristata) Brain in Response to Hypoxia and Reoxygenation

When the brain goes diving: transcriptome analysis reveals a reduced aerobic energy metabolism and increased stress proteins in the seal brain

(2016) Andrej Fabrizius et al.   BMC GENOMICS

An atypical distribution of lactate dehydrogenase isoenzymes in the hooded seal (Cystophora cristata) brain may reflect a biochemical adaptation to diving

(2016) Mariana Leivas Müller Hoff et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Synaptic transmission despite severe hypoxia in hippocampal slices of the deep-diving hooded seal

(2016) Samuel J. Geiseler et al.   NEUROSCIENCE

Tissue hypoxia during ischemic stroke: Adaptive clues from hypoxia-tolerant animal models

(2015) Thomas I. Nathaniel et al.   BRAIN RESEARCH BULLETIN

Convergent evolution of the genomes of marine mammals

(2015) Andrew D Foote et al.   NATURE GENETICS

MCT4-Mediated Expression of EAAT1 is Involved in the Resistance to Hypoxia Injury in Astrocyte–Neuron co-Cultures

(2015) Chen Gao et al.   NEUROCHEMICAL RESEARCH

Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity

(2014) Daisuke Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

No oxygen? No problem! Intrinsic brain tolerance to hypoxia in vertebrates

(2014) J. Larson et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Decreased Astroglial Monocarboxylate Transporter 4 Expression in Temporal Lobe Epilepsy

(2014) Bei Liu et al.   MOLECULAR NEUROBIOLOGY

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease

(2014) Xinxia Peng et al.   NATURE BIOTECHNOLOGY

Intermittent Hypoxia Preconditioning-Induced Epileptic Tolerance by Upregulation of Monocarboxylate Transporter 4 Expression in Rat Hippocampal Astrocytes

(2014) Chen Gao et al.   NEUROCHEMICAL RESEARCH

The role of glycogen, glucose and lactate in neuronal activity during hypoxia in the hooded seal (Cystophora cristata) brain

(2014) N.U. Czech-Damal et al.   NEUROSCIENCE

Cerebral and Hepatic Inflammatory Response after Neonatal Hypoxia-Ischemia in Newborn Rats

(2013) H.J.C. Bonestroo et al.   DEVELOPMENTAL NEUROSCIENCE

A review of the multi-level adaptations for maximizing aerobic dive duration in marine mammals: from biochemistry to behavior

(2013) Randall W. Davis   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Neuroglobin of seals and whales: Evidence for a divergent role in the diving brain

(2012) M. Schneuer et al.   NEUROSCIENCE

Selective brain cooling and its vascular basis in diving seals

(2010) A. S. Blix et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Slow intrinsic oscillations in thick neocortical slices of hypoxia tolerant deep diving seals

(2010) J.-M. Ramirez et al.   NEUROSCIENCE

Extreme hypoxemic tolerance and blood oxygen depletion in diving elephant seals

(2009) Jessica U. Meir et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

When the brain goes diving: glial oxidative metabolism may confer hypoxia tolerance to the seal brain

(2009) S.A. Mitz et al.   NEUROSCIENCE

Genomic response of the rat brain to global ischemia and reperfusion

(2008) Fabian Büttner et al.   BRAIN RESEARCH

Remarkable neuronal hypoxia tolerance in the deep-diving adult hooded seal (Cystophora cristata)

(2008) Lars P. Folkow et al.   NEUROSCIENCE LETTERS

Running, swimming and diving modifies neuroprotecting globins in the mammalian brain

(2007) T. M Williams et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES