The CCL2/CCR2 Axis Affects Transmigration and Proliferation but Not Resistance to Chemotherapy of Acute Myeloid Leukemia Cells

A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic Regulators

(2016) Annette K. Brenner et al.   Frontiers in Immunology

Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF- B mediates chemoresistance

(2014) R. Jacamo et al.   BLOOD

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

(2014) Terrence N. Wong et al.   NATURE

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

(2014) Laura Bonapace et al.   NATURE

A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia

(2012) G. L. Uy et al.   BLOOD

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis

(2012) Patricia Macanas-Pirard et al.   PLoS One

CCR2 Acts as Scavenger for CCL2 during Monocyte Chemotaxis

(2012) Silvia Volpe et al.   PLoS One

CCL2/MCP-1 modulation of microglial activation and proliferation

(2011) Ara E Hinojosa et al.   Journal of Neuroinflammation

The roles of MCP-1 and protein kinase Cδ activation in human eosinophilic leukemia EoL-1 cells

(2009) Ji-Sook Lee et al.   CYTOKINE

Therapeutic targeting of microenvironmental interactions in leukemia: Mechanisms and approaches

(2009) Marina Konopleva et al.   DRUG RESISTANCE UPDATES

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

(2008) B. Nervi et al.   BLOOD

Monocyte chemoattractant protein-1: A key mediator in inflammatory processes

(2008) Esther Melgarejo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation

(2008) S Tavor et al.   LEUKEMIA

CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

(2008) J A Burger et al.   LEUKEMIA