Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling

Hepatitis C virus regulates the production of monocytic myeloid-derived suppressor cells from peripheral blood mononuclear cells through PI3K pathway and autocrine signaling

(2016) Xiaoli Pang et al.   CLINICAL IMMUNOLOGY

Indolamine 2,3-dioxygenase expression by monocytes and dendritic cell populations in hepatitis C patients

(2015) S. Schulz et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

PI3kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization

(2015) Marwan Mounayar et al.   STEM CELLS

CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs

(2014) R. Jitschin et al.   BLOOD

An unbalanced PD-L1/CD86 ratio in CD14++CD16+ monocytes is correlated with HCV viremia during chronic HCV infection

(2014) Jiajia Zheng et al.   Cellular & Molecular Immunology

Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in chronic hepatitis C patients

(2014) Naicui Zhai et al.   Cellular & Molecular Immunology

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

(2014) Daniela C. Ifrim et al.   Clinical and Vaccine Immunology

New Hepatitis C Therapies: The Toolbox, Strategies, and Challenges

(2014) Jean–Michel Pawlotsky   GASTROENTEROLOGY

Dopamine inhibits the function of Gr-1+ CD115+ myeloid-derived suppressor cells through D1-like receptors and enhances anti-tumor immunity

(2014) Jin Wu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Myeloid-Derived Suppressor Cells Are Associated with Viral Persistence and Downregulation of TCR ζ Chain Expression on CD8+ T Cells in Chronic Hepatitis C Patients

(2014) Qing-Lei Zeng et al.   MOLECULES AND CELLS

The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia

(2013) D. Brusa et al.   HAEMATOLOGICA

STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients

(2013) David Vasquez-Dunddel et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies

(2013) Li Shi et al.   Journal of Hematology & Oncology

Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity

(2013) Qiang Ding et al.   JOURNAL OF HEPATOLOGY

Antigen-Specific CD4+ T Cells Regulate Function of Myeloid-Derived Suppressor Cells in Cancer via Retrograde MHC Class II Signaling

(2012) S. Nagaraj et al.   CANCER RESEARCH

Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection

(2012) Koyo Higashitani et al.   JOURNAL OF GASTROENTEROLOGY

Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species

(2011) Robert S. Tacke et al.   HEPATOLOGY

HCV core and NS3 proteins manipulate human blood-derived dendritic cell development and promote Th 17 differentiation

(2011) Zhengkun Tu et al.   INTERNATIONAL IMMUNOLOGY

Extracellular Hepatitis C Virus Core Protein Activates STAT3 in Human Monocytes/Macrophages/Dendritic Cells via an IL-6 Autocrine Pathway

(2011) Robert S. Tacke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HCV-Related Proteins Activate Kupffer Cells Isolated from Human Liver Tissues

(2010) Naohiro Hosomura et al.   DIGESTIVE DISEASES AND SCIENCES

PD-1 and PD-L1 upregulation promotes CD8+ T-cell apoptosis and postoperative recurrence in hepatocellular carcinoma patients

(2010) Feng Shi et al.   INTERNATIONAL JOURNAL OF CANCER

Interferon- -triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells

(2009) B. Jurgens et al.   BLOOD

Hepatitis C Virus Core Protein Subverts the Antiviral Activities of Human Kupffer Cells

(2009) Zhengkun Tu et al.   GASTROENTEROLOGY

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

(2009) Loise M. Francisco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of Stat3 in suppressing anti-tumor immunity

(2008) Marcin Kortylewski et al.   CURRENT OPINION IN IMMUNOLOGY