Cytosolic RNA:DNA Duplexes Generated by Endogenous Reverse Transcriptase Activity as Autonomous Inducers of Skin Inflammation in Psoriasis

T cell responses in psoriasis and psoriatic arthritis

(2015) Marco Diani et al.   AUTOIMMUNITY REVIEWS

Genetics of Psoriasis

(2015) Satveer K. Mahil et al.   DERMATOLOGIC CLINICS

Patterns and functional roles of LINE-1 and Alu methylation in the keratinocyte from patients with psoriasis vulgaris

(2015) Surasak Yooyongsatit et al.   JOURNAL OF HUMAN GENETICS

Genetic and epigenetic basis of psoriasis pathogenesis

(2015) Aditi Chandra et al.   MOLECULAR IMMUNOLOGY

Mechanisms of inflammasome activation: recent advances and novel insights

(2015) Sivapriya K. Vanaja et al.   TRENDS IN CELL BIOLOGY

Human Endogenous Retrovirus (HERV-K) Reverse Transcriptase as a Breast Cancer Prognostic Marker

(2015) Maya Golan et al.   NEOPLASIA

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

(2014) R. E. Rigby et al.   EMBO JOURNAL

Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA

(2014) Roberto Lande et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA

(2014) S. Chiliveru et al.   JOURNAL OF IMMUNOLOGY

The enemy within: endogenous retroelements and autoimmune disease

(2014) Hannah E Volkman et al.   NATURE IMMUNOLOGY

Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity

(2014) B. J. Fowler et al.   SCIENCE

Immune sensing of nucleic acids in inflammatory skin diseases

(2014) Olivier Demaria et al.   Seminars in Immunopathology

Out of Balance: R-loops in Human Disease

(2014) Matthias Groh et al.   PLoS Genetics

Is chronic plaque psoriasis triggered by microbiota in the skin?

(2013) L. Fry et al.   BRITISH JOURNAL OF DERMATOLOGY

A Toll-Like Receptor 7, 8, and 9 Antagonist Inhibits Th1 and Th17 Responses and Inflammasome Activation in a Model of IL-23-Induced Psoriasis

(2013) Weiwen Jiang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

How should we approach classification of autoinflammatory diseases?

(2013) Gilles Grateau et al.   Nature Reviews Rheumatology

Suppression of Molecular Inflammatory Pathways by Toll-Like Receptor 7, 8, and 9 Antagonists in a Model of IL-23-Induced Skin Inflammation

(2013) Mayte Suárez-Fariñas et al.   PLoS One

Endogenous retroelements and autoimmune disease

(2012) Daniel B Stetson   CURRENT OPINION IN IMMUNOLOGY

Strong induction of AIM2 expression in human epidermis in acute and chronic inflammatory skin conditions

(2012) Heleen D. de Koning et al.   EXPERIMENTAL DERMATOLOGY

Mechanisms and emerging functions of DNA degradation in the epidermis

(2012) Leopold Eckhart   Frontiers in Bioscience-Landmark

Comparison of bacterial microbiota in skin biopsies from normal and psoriatic skin

(2011) Annika Fahlén et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Characterization and comparison of telomere length, telomerase and reverse transcriptase activity and gene expression in human mesenchymal stem cells and cancer cells of various origins

(2011) Byeong-Gyun Jeon et al.   CELL AND TISSUE RESEARCH

Pathogenic DNA: Cytosolic DNA promotes inflammation in psoriasis

(2011) Jürgen Schauber et al.   CELL CYCLE

Human keratinocytes express AIM2 and respond to dsDNA with IL-1β secretion

(2011) Verena Kopfnagel et al.   EXPERIMENTAL DERMATOLOGY

Chemical Induction of Endogenous Retrovirus Particles from the Vero Cell Line of African Green Monkeys

(2011) H. Ma et al.   JOURNAL OF VIROLOGY

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

(2011) Y. Dombrowski et al.   Science Translational Medicine

HIV-associated psoriasis: pathogenesis, clinical features, and management

(2010) Nilesh Morar et al.   LANCET INFECTIOUS DISEASES

Apurinic/Apyrimidinic Endonuclease 1 Is a Key Modulator of Keratinocyte Inflammatory Responses

(2009) H.-M. Lee et al.   JOURNAL OF IMMUNOLOGY