Comparison of In-Vitro and Ex-Vivo Wound Healing Assays for the Investigation of Diabetic Wound Healing and Demonstration of a Beneficial Effect of a Triterpene Extract
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Title
Comparison of In-Vitro and Ex-Vivo Wound Healing Assays for the Investigation of Diabetic Wound Healing and Demonstration of a Beneficial Effect of a Triterpene Extract
Authors
Keywords
Glucose, Keratinocytes, Diabetes mellitus, Fibroblasts, Wound healing, Cytokines, Drug screening, Epidermis
Journal
PLoS One
Volume 12, Issue 1, Pages e0169028
Publisher
Public Library of Science (PLoS)
Online
2017-01-10
DOI
10.1371/journal.pone.0169028
References
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- High-Glucose Environment Enhanced Oxidative Stress and Increased Interleukin-8 Secretion From Keratinocytes: New Insights Into Impaired Diabetic Wound Healing
- (2013) C.-C. E. Lan et al. DIABETES
- Cell motility in models of wounded human skin is improved by Gap27 despite raised glucose, insulin and IGFBP-5
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- In vitro cell migration and invasion assays
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- Somatostatin Inhibits Cell Migration and Reduces Cell Counts of Human Keratinocytes and Delays Epidermal Wound Healing in an Ex Vivo Wound Model
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