Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis

Phosphorylation of Fe65 amyloid precursor protein-binding protein in response to neuronal differentiation

(2016) Niina A. Koistinen et al.   NEUROSCIENCE LETTERS

Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing

(2015) W. N. V. Chow et al.   BIOCHEMICAL JOURNAL

Fe65 Ser228is phosphorylated by ATM/ATR and inhibits Fe65–APP-mediated gene transcription

(2015) Paul A. Jowsey et al.   BIOCHEMICAL JOURNAL

ApoE4 and A  Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation

(2015) A. Sen et al.   JOURNAL OF NEUROSCIENCE

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Regulation Fe65 localization to the nucleus by SGK1 phosphorylation of its Ser566 residue

(2011) Eun-Jeoung Lee et al.   BMB Reports

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

Insulin-like Growth Factor-1 (IGF-1)-induced Processing of Amyloid-β Precursor Protein (APP) and APP-like Protein 2 Is Mediated by Different Metalloproteinases

(2010) Kristin T. Jacobsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway

(2009) Z. V. Goodger et al.   JOURNAL OF CELL SCIENCE

Structural and functional characterization of a novel FE65 protein product up-regulated in cognitively impaired FE65 knockout mice

(2009) Bethany H. Cool et al.   JOURNAL OF NEUROCHEMISTRY

Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2

(2008) Jens Radzimanowski et al.   EMBO REPORTS

Crystal Structure of the Human Fe65-PTB1 Domain

(2008) Jens Radzimanowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY