EGR1 Regulates Transcription Downstream of Mechanical Signals during Tendon Formation and Healing

The transcription factor scleraxis is a critical regulator of cardiac fibroblast phenotype

(2016) Rushita A. Bagchi et al.   BMC BIOLOGY

EGR1 Induces Tenogenic Differentiation of Tendon Stem Cells and Promotes Rabbit Rotator Cuff Repair

(2015) Xu Tao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tendon mechanobiology:Current knowledge and future research opportunities

(2015) Michael Lavagnino et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Tendon injury: from biology to tendon repair

(2015) Geoffroy Nourissat et al.   Nature Reviews Rheumatology

Mohawk Promotes the Tenogenesis of Mesenchymal Stem Cells Through Activation of the TGFβ Signaling Pathway

(2015) Huanhuan Liu et al.   STEM CELLS

Loss of Tenomodulin Results in Reduced Self-Renewal and Augmented Senescence of Tendon Stem/Progenitor Cells

(2015) Paolo Alberton et al.   STEM CELLS AND DEVELOPMENT

Fibrin Gels Exhibit Improved Biological, Structural, and Mechanical Properties Compared with Collagen Gels in Cell-Based Tendon Tissue-Engineered Constructs

(2015) Andrew P. Breidenbach et al.   TISSUE ENGINEERING PART A

Chick tendon fibroblast transcriptome and shape depend on whether the cell has made its own collagen matrix

(2015) Ching-Yan Chloé Yeung et al.   Scientific Reports

Comparative analysis of mesenchymal stem cell and embryonic tendon progenitor cell response to embryonic tendon biochemical and mechanical factors

(2015) Jeffrey P Brown et al.   Stem Cell Research & Therapy

Transcriptomic analysis of mouse limb tendon cells during development

(2014) E. Havis et al.   DEVELOPMENT

Release of Tensile Strain on Engineered Human Tendon Tissue Disturbs Cell Adhesions, Changes Matrix Architecture, and Induces an Inflammatory Phenotype

(2014) Monika L. Bayer et al.   PLoS One

Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament

(2013) Y. Sugimoto et al.   DEVELOPMENT

One load to rule them all: Mechanical control of the musculoskeletal system in development and aging

(2013) Yulia Shwartz et al.   DIFFERENTIATION

Primary gene response to mechanical loading in healing rat Achilles tendons

(2013) Pernilla Eliasson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Microtrauma stimulates rat Achilles tendon healing via an early gene expression pattern similar to mechanical loading

(2013) Malin Hammerman et al.   JOURNAL OF APPLIED PHYSIOLOGY

Embryonic mechanical and soluble cues regulate tendon progenitor cell gene expression as a function of developmental stage and anatomical origin

(2013) Jeffrey P Brown et al.   JOURNAL OF BIOMECHANICS

Transcription factor EGR1 directs tendon differentiation and promotes tendon repair

(2013) Marie-Justine Guerquin et al.   JOURNAL OF CLINICAL INVESTIGATION

Smad3 binds scleraxis and mohawk and regulates tendon matrix organization

(2013) Ellora Berthet et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Dynamic Compression of Chondrocyte-Agarose Constructs Reveals New Candidate Mechanosensitive Genes

(2012) Carole Bougault et al.   PLoS One

Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals

(2011) Toru Maeda et al.   CURRENT BIOLOGY

Ultrasound and microbubble-assisted gene delivery in Achilles tendons: Long lasting gene expression and restoration of fibromodulin KO phenotype

(2011) Anthony Delalande et al.   JOURNAL OF CONTROLLED RELEASE

Tendon Biomechanics and Mechanobiology—A Minireview of Basic Concepts and Recent Advancements

(2011) James H-C. Wang et al.   Journal of Hand Therapy

Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts

(2011) Christopher L. Mendias et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The initiation of embryonic-like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tension

(2010) Monika L. Bayer et al.   BIOMATERIALS

Induction ofSirt1by Mechanical Stretch of Skeletal Muscle through the Early Response Factor EGR1 Triggers an Antioxidative Response

(2010) Patricia S. Pardo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EGR1 and EGR2 Involvement in Vertebrate Tendon Differentiation

(2010) Véronique Lejard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Scleraxis expression is coordinately regulated in a murine model of patellar tendon injury

(2010) Alexander Scott et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Synthesis of embryonic tendon-like tissue by human marrow stromal/mesenchymal stem cells requires a three-dimensional environment and transforming growth factor β3

(2010) Zoher Kapacee et al.   MATRIX BIOLOGY

Mechano-Sensitive Transcriptional Factor Egr-1 Regulates Insulin-Like Growth Factor-1 Receptor Expression and Contributes to Neointima Formation in Vein Grafts

(2009) Xiaoqian Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Recruitment and maintenance of tendon progenitors by TGF  signaling are essential for tendon formation

(2009) B. A. Pryce et al.   DEVELOPMENT

Rat Achilles tendon healing: mechanical loading and gene expression

(2009) Pernilla Eliasson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Tension is required for fibripositor formation

(2008) Z KAPACEE et al.   MATRIX BIOLOGY

Expression of transforming growth factor β isoforms and their roles in tendon healing

(2008) Kai-Ming Chan et al.   WOUND REPAIR AND REGENERATION