Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins

Implication of the Immune System in Alzheimer's Disease: Evidence from Genome-Wide Pathway Analysis

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ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

(2016) Agnieszka Mamińska et al.   Science Signaling

ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors

(2016) Agnieszka Mamińska et al.   Science Signaling

The BioPlex Network: A Systematic Exploration of the Human Interactome

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CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

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PRR-signaling pathways: Learning from microbial tactics

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A Proteome-Scale Map of the Human Interactome Network

(2014) Thomas Rolland et al.   CELL

A Genome-wide Small Interfering RNA (siRNA) Screen Reveals Nuclear Factor-κB (NF-κB)-independent Regulators of NOD2-induced Interleukin-8 (IL-8) Secretion

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Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

(2014) I. J. McGough et al.   JOURNAL OF CELL SCIENCE

 -PIX and Rac1 GTPase Mediate Trafficking and Negative Regulation of NOD2

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Endosomes are specialized platforms for bacterial sensing and NOD2 signalling

(2014) Norihiro Nakamura et al.   NATURE

The BioGRID interaction database: 2015 update

(2014) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

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Insights into the molecular basis of the NOD2 signalling pathway

(2014) J. P. Boyle et al.   Open Biology

A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses

(2013) Maureen Menning et al.   FEBS LETTERS

Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge

(2013) H. Fukuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-Wide siRNA Screen Reveals Positive and Negative Regulators of the NOD2 and NF- B Signaling Pathways

(2013) N. Warner et al.   Science Signaling

The intermediate filament protein, vimentin, is a regulator of NOD2 activity

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A Dual Role for Receptor-interacting Protein Kinase 2 (RIP2) Kinase Activity in Nucleotide-binding Oligomerization Domain 2 (NOD2)-dependent Autophagy

(2012) Craig R. Homer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

TRIM27 Negatively Regulates NOD2 by Ubiquitination and Proteasomal Degradation

(2012) Birte Zurek et al.   PLoS One

TLE1 Modifies the Effects of NOD2 in the Pathogenesis of Crohn's Disease

(2011) Elaine R. Nimmo et al.   GASTROENTEROLOGY

Toward an understanding of the protein interaction network of the human liver

(2011) J. Wang et al.   Molecular Systems Biology

RIP2 polymorphisms in inflammatory bowel diseases

(2010) R. Thiébaut et al.   INFLAMMATORY BOWEL DISEASES

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

(2010) Beate Neumann et al.   NATURE

Membrane budding and scission by the ESCRT machinery: it's all in the neck

(2010) James H. Hurley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expanding the Substantial Interactome of NEMO Using Protein Microarrays

(2010) Beau J. Fenner et al.   PLoS One

Intermediate vimentin filaments and their role in intracellular organelle distribution

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A dynamic network of transcription in LPS-treated human subjects

(2009) Junhee Seok et al.   BMC Systems Biology

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway

(2009) Elsa Lauwers et al.   JOURNAL OF CELL BIOLOGY

The role of TLRs, NLRs and RLRs in mucosal innate immunity and homeostasis

(2009) E C Lavelle et al.   Mucosal Immunology

A Crohn's disease–associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1

(2009) Eiichiro Noguchi et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Towards a molecular risk map—Recent advances on the etiology of inflammatory bowel disease

(2009) Philip Rosenstiel et al.   SEMINARS IN IMMUNOLOGY

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

(2009) Juan C. Salazar et al.   PLoS Pathogens

Genetic Analysis of Innate Immunity in Crohn's Disease and Ulcerative Colitis Identifies Two Susceptibility Loci Harboring CARD9 and IL18RAP

(2008) Alexandra Zhernakova et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Analysis in Sarcoidosis and Crohn's Disease Unravels a Common Susceptibility Locus on 10p12.2

(2008) Andre Franke et al.   GASTROENTEROLOGY

Novel Interactions of ESCRT-III with LIP5 and VPS4 and their Implications for ESCRT-III Disassembly

(2008) Soomin Shim et al.   MOLECULAR BIOLOGY OF THE CELL

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

(2008) Subra Kugathasan et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1  secretion in response to Bacillus anthracis infection and muramyl dipeptide

(2008) L.-C. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: A yeast two-hybrid approach

(2008) Subhash Thalappilly et al.   PROTEOMICS