Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion

Urokinase receptor and resistance to targeted anticancer agents

(2015) Steven L. Gonias et al.   Frontiers in Pharmacology

A Urokinase Receptor-Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma

(2014) J. Wykosky et al.   CANCER RESEARCH

uPAR Targeted Radionuclide Therapy with 177Lu-DOTA-AE105 Inhibits Dissemination of Metastatic Prostate Cancer

(2014) Morten Persson et al.   MOLECULAR PHARMACEUTICS

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

(2014) J Hu et al.   ONCOGENE

Concomitant treatment with pertussis toxin plus temozolomide increases the survival of rats bearing intracerebral RG2 glioma

(2013) Roxana Magaña-Maldonado et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

(2012) Andrej Pala et al.   Cancers

Development of Novel Therapeutics Targeting the Urokinase Plasminogen Activator Receptor (uPAR) and Their Translation Toward the Clinic

(2011) Andrew P. Mazar et al.   CURRENT PHARMACEUTICAL DESIGN

The ins and outs of pertussis toxin

(2011) Camille Locht et al.   FEBS Journal

Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin

(2011) Mario Orozco-Morales et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells

(2011) J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α

(2010) Sascha Seidel et al.   BRAIN

Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts

(2010) Magdalena Ksiazkiewicz et al.   IMMUNOBIOLOGY

Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence

(2010) A. Mukasa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The urokinase receptor as an entertainer of signal transduction

(2009) Silvia D'Alessio   Frontiers in Bioscience-Landmark

Regulation of cell signalling by uPAR

(2009) Harvey W. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87

(2008) Shi-cang Yu et al.   CANCER LETTERS