Cantharidin Induced Oral Squamous Cell Carcinoma Cell Apoptosis via the JNK-Regulated Mitochondria and Endoplasmic Reticulum Stress-Related Signaling Pathways
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Title
Cantharidin Induced Oral Squamous Cell Carcinoma Cell Apoptosis via the JNK-Regulated Mitochondria and Endoplasmic Reticulum Stress-Related Signaling Pathways
Authors
Keywords
Apoptosis, Protein expression, Mitochondria, Stress signaling cascade, Transfection, Apoptotic signaling cascade, Carcinomas, Tongue
Journal
PLoS One
Volume 11, Issue 12, Pages e0168095
Publisher
Public Library of Science (PLoS)
Online
2016-12-09
DOI
10.1371/journal.pone.0168095
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Note: Only part of the references are listed.- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- A novel cantharidin analog N-Benzylcantharidinamide reduces the expression of MMP-9 and invasive potentials of Hep3B via inhibiting cytosolic translocation of HuR
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- (2013) Yi-Ping Zhan et al. Asian Pacific Journal of Cancer Prevention
- Apoptosis of Colorectal Cancer UTC116 Cells Induced by Cantharidinate
- (2013) Bin Liu et al. Asian Pacific Journal of Cancer Prevention
- Cantharidin-Based Small Molecules as Potential Therapeutic Agents
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- Cucurbitacin E as Inducer of Cell Death and Apoptosis in Human Oral Squamous Cell Carcinoma Cell Line SAS
- (2013) Chao-Ming Hung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2013) Surya B. Prasad et al. MICROSCOPY AND MICROANALYSIS
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- (2013) Tien-Hui Lu et al. TOXICOLOGY LETTERS
- Paraquat induces lung alveolar epithelial cell apoptosis via Nrf-2-regulated mitochondrial dysfunction and ER stress
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- Tissue inhibitor of metalloproteinases in oral squamous cell carcinomas – A therapeutic target?
- (2012) Mario Pérez-Sayáns García et al. CANCER LETTERS
- Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway
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- Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals
- (2012) Chun-Hung Chen et al. TOXICOLOGY
- Prognostic Value of Lymph Node Density in Node-Positive Patients with Oral Squamous Cell Carcinoma
- (2011) Sang Yoon Kim et al. ANNALS OF SURGICAL ONCOLOGY
- Apoptosis-related protein-2 triggers melanoma cell death by a mechanism including both endoplasmic reticulum stress and mitochondrial dysregulation
- (2011) D. Selimovic et al. CARCINOGENESIS
- Prognostic significance of immunohistochemical biomarkers in oral squamous cell carcinoma
- (2011) L.R. Oliveira et al. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
- Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology
- (2011) Newell W. Johnson et al. PERIODONTOLOGY 2000
- Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury
- (2011) Tien-Hui Lu et al. TOXICOLOGY LETTERS
- JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative
- (2010) Dong-Myung Kim et al. APOPTOSIS
- Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis
- (2010) Wei Li et al. CANCER SCIENCE
- Chemopreventive Potential of Natural Compounds in Head and Neck Cancer
- (2010) Mohammad Aminur Rahman et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Potential biomarkers in saliva for oral squamous cell carcinoma
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- Therapeutic targeting of apoptosis pathways in cancer
- (2009) David S Ziegler et al. CURRENT OPINION IN ONCOLOGY
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