RAS–Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers
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Title
RAS–Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers
Authors
Keywords
MAPK signaling cascades, Lung and intrathoracic tumors, STAT signaling, Adenocarcinoma of the lung, Adenocarcinoma cells, Gene expression, Luciferase, Squamous cell lung carcinoma
Journal
PLoS One
Volume 11, Issue 11, Pages e0166626
Publisher
Public Library of Science (PLoS)
Online
2016-11-16
DOI
10.1371/journal.pone.0166626
References
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- (2015) Suzanne L. Topalian et al. CANCER CELL
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- (2014) K. Azuma et al. ANNALS OF ONCOLOGY
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- (2014) M. Atefi et al. CLINICAL CANCER RESEARCH
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- (2014) Siwen Hu-Lieskovan et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Posttransplant Lymphoproliferative Disorders: Implications for Targeted Therapy
- (2012) M. R. Green et al. CLINICAL CANCER RESEARCH
- The Activation of MAPK in Melanoma Cells Resistant to BRAF Inhibition Promotes PD-L1 Expression That Is Reversible by MEK and PI3K Inhibition
- (2012) X. Jiang et al. CLINICAL CANCER RESEARCH
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-L1 expression on tolerogenic APCs is controlled by STAT-3
- (2010) Sabine J. Wölfle et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- B7-H1 expression is regulated by MEK/ERK signaling pathway in anaplastic large cell lymphoma and Hodgkin lymphoma
- (2009) Ryo Yamamoto et al. CANCER SCIENCE
- In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression
- (2009) Corbin E Meacham et al. NATURE GENETICS
- Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)
- (2008) M. Marzec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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