Cell Division Cycle 6 Promotes Mitotic Slippage and Contributes to Drug Resistance in Paclitaxel-Treated Cancer Cells

Cdc6 and Cyclin E2 Are PTEN-Regulated Genes Associated with Human Prostate Cancer Metastasis

(2015) Zhong Wu et al.   NEOPLASIA

Taxanes in cancer of the head and neck

(2014) Krzysztof Misiukiewicz et al.   ANTI-CANCER DRUGS

Drug discovery targeting cell division proteins, microtubules and FtsZ

(2014) Iwao Ojima et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle

(2014) Yanting Zhu et al.   CELL CYCLE

CDC6 controls dynamics of the first embryonic M-phase entry and progression via CDK1 inhibition

(2014) Mohammed El Dika et al.   DEVELOPMENTAL BIOLOGY

Norcantharidin Inhibits Pre-Replicative Complexes Assembly of HepG2 Cells

(2013) Sansan Chen et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Targeting mitotic exit with hyperthermia or APC/C inhibition to increase paclitaxel efficacy

(2013) Serena Giovinazzi et al.   CELL CYCLE

Generation of cancer stem-like cells through the formation of polyploid giant cancer cells

(2013) S Zhang et al.   ONCOGENE

Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1

(2012) Shuijun Zhang et al.   CELLULAR SIGNALLING

Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction

(2011) M. Luz Flores et al.   BREAST CANCER RESEARCH AND TREATMENT

Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics

(2011) J. D. Orth et al.   CANCER RESEARCH

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase

(2010) H. Yim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways

(2009) Po-Cheng Chiang et al.   BIOCHEMICAL PHARMACOLOGY

Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly

(2009) Hsiao-Chun Huang et al.   CANCER CELL

Separase Is Recruited to Mitotic Chromosomes to Dissolve Sister Chromatid Cohesion in a DNA-Dependent Manner

(2009) Yuxiao Sun et al.   CELL

Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit

(2009) M. E. Bekier et al.   MOLECULAR CANCER THERAPEUTICS

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied

(2008) Daniela A. Brito et al.   JOURNAL OF CELL BIOLOGY

Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

(2008) Z N Demidenko et al.   ONCOGENE