11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored

Adrenal-derived 11-oxygenated 19-carbon steroids are the dominant androgens in classic 21-hydroxylase deficiency

(2016) Adina F Turcu et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The 5α-Androstanedione Pathway to Dihydrotestosterone in Castration-Resistant Prostate Cancer

(2016) Nima Sharifi   JOURNAL OF INVESTIGATIVE MEDICINE

11β-hydroxyandrostenedione: Downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways

(2015) Amanda C. Swart et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer

(2015) Zhenfei Li et al.   NATURE

Androstenedione Is the Preferred Androgen Source in Hormone Refractory Prostate Cancer--Letter

(2014) N. Sharifi et al.   CLINICAL CANCER RESEARCH

A comparative study of the androgenic properties of progesterone and the progestins, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A)

(2014) Donita J. Africander et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Liquid Chromatography–Tandem Mass Spectrometry Analysis of Human Adrenal Vein 19-Carbon Steroids Before and After ACTH Stimulation

(2013) Juilee Rege et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

11β-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione

(2013) Amanda C. Swart et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?

(2013) Karl-Heinz Storbeck et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

11β-Hydroxyandrostenedione Returns to the Steroid Arena: Biosynthesis, Metabolism and Function

(2013) Liezl Bloem et al.   MOLECULES

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study

(2012) Karim Fizazi et al.   LANCET ONCOLOGY

Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy

(2012) Howard I. Scher et al.   NEW ENGLAND JOURNAL OF MEDICINE

Steroid biosynthesis and prostate cancer

(2012) Nima Sharifi et al.   STEROIDS

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

(2011) C. Cai et al.   CANCER RESEARCH

Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract

(2011) Donita Africander et al.   CONTRACEPTION

The influence of Aspalathus linearis (Rooibos) and dihydrochalcones on adrenal steroidogenesis: Quantification of steroid intermediates and end products in H295R cells

(2011) Lindie Schloms et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Abiraterone and Increased Survival in Metastatic Prostate Cancer

(2011) Johann S. de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of Androgen Receptor Signaling in Hormonal Therapy-Resistant Prostate Cancer Cell Lines

(2011) Rute B. Marques et al.   PLoS One

Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer

(2011) K.-H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Androgens Suppress EZH2 Expression Via Retinoblastoma (RB) and p130-Dependent Pathways: A Potential Mechanism of Androgen-Refractory Progression of Prostate Cancer

(2010) Laura R. Bohrer et al.   ENDOCRINOLOGY

Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

(2010) Karen E. Knudsen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Steroid Hormone Receptors in Prostate Cancer: A Hard Habit to Break?

(2009) Gerhardt Attard et al.   CANCER CELL

Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer

(2009) Gerhardt Attard et al.   JOURNAL OF CLINICAL ONCOLOGY

Androgen-Responsive Gene Database: Integrated Knowledge on Androgen-Responsive Genes

(2009) Mei Jiang et al.   MOLECULAR ENDOCRINOLOGY

Proteomic Interrogation of Androgen Action in Prostate Cancer Cells Reveals Roles of Aminoacyl tRNA Synthetases

(2009) Adaikkalam Vellaichamy et al.   PLoS One

A simple method to measure cell viability in proliferation and cytotoxicity assays

(2009) Ricardo Carneiro Borra et al.   Brazilian Oral Research

Androgen biosynthetic pathways in the human prostate

(2008) Van Luu-The et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Efficacy of androgen deprivation therapy (ADT) in patients with advanced prostate cancer

(2008) Robert W. Ross et al.   CANCER

TMPRSS2:ERG Fusion Identifies a Subgroup of Prostate Cancers with a Favorable Prognosis

(2008) O. R. Saramaki et al.   CLINICAL CANCER RESEARCH

International epidemiology of prostate cancer: Geographical distribution and secular trends

(2008) Peter D. Baade et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes

(2008) Bo-Ying Bao et al.   PROSTATE

Mechanisms mediating androgen receptor reactivation after castration

(2008) Xin Yuan et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Cyp11b1 Is Induced in the Murine Gonad by Luteinizing Hormone/Human Chorionic Gonadotropin and Involved in the Production of 11-Ketotestosterone, a Major Fish Androgen: Conservation and Evolution of the Androgen Metabolic Pathway

(2007) Takashi Yazawa et al.   ENDOCRINOLOGY