miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington’s Disease Monkey Neural Cells

The Potential Regulatory Mechanisms of miR-196a in Huntington’s Disease through Bioinformatic Analyses

(2015) Mu-Hui Fu et al.   PLoS One

Involvement of miR-196a in HIV-associated neurocognitive disorders

(2014) Asen Bagashev et al.   APOPTOSIS

A two years longitudinal study of a transgenic Huntington disease monkey

(2014) Anthony WS Chan et al.   BMC NEUROSCIENCE

Ubiquitin-Activating Enzyme Activity Contributes to Differential Accumulation of Mutant Huntingtin in Brain and Peripheral Tissues

(2014) B. E. Wade et al.   JOURNAL OF NEUROSCIENCE

FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain

(2014) Ying Li et al.   Molecular BioSystems

HD CAGnome: A Search Tool for Huntingtin CAG Repeat Length-Correlated Genes

(2014) Ekaterina I. Galkina et al.   PLoS One

microRNA-128a dysregulation in transgenic Huntington’s disease monkeys

(2014) Jannet Kocerha et al.   Molecular Brain

MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis

(2014) Andrew G. Hoss et al.   PLoS Genetics

Reversal of Cellular Phenotypes in Neural Cells Derived from Huntington’s Disease Monkey-Induced Pluripotent Stem Cells

(2014) Richard L. Carter et al.   Stem Cell Reports

In silico analysis of regulatory networks underlines the role of miR-10b-5p and its target BDNF in huntington’s disease

(2014) Sören Müller   Translational Neurodegeneration

miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models

(2013) Pei-Hsun Cheng et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Low Annexin A1 expression predicts benefit from induction chemotherapy in oral cancer patients with moderate or poor pathologic differentiation grade

(2013) Dong-wang Zhu et al.   BMC CANCER

MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation

(2013) Patricia Severino et al.   BMC CANCER

Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys

(2013) Jannet Kocerha et al.   BMC NEUROSCIENCE

Gene expression profile in fibroblasts of Huntington's disease patients and controls

(2013) Eleonora Marchina et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin

(2013) Youngnam N. Jin et al.   PLoS One

Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington’s Disease

(2013) Carmela Giampà et al.   PLoS One

A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington’s disease in mice

(2013) Aníbal I. Acuña et al.   Nature Communications

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

(2012) Dongbo Yu et al.   CELL

Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes

(2012) The HD iPSC Consortium   Cell Stem Cell

Annexin-1-mediated Endothelial Cell Migration and Angiogenesis Are Regulated by Vascular Endothelial Growth Factor (VEGF)-induced Inhibition of miR-196a Expression

(2012) Anne-Laure Pin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease

(2012) Chiara Soldati et al.   JOURNAL OF NEUROCHEMISTRY

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2

(2012) Yu Miyazaki et al.   NATURE MEDICINE

Quantitative Proteomic Analysis of Human Substantia Nigra in Alzheimer’s Disease, Huntington’s Disease and Multiple Sclerosis

(2012) Sheng Chen et al.   NEUROCHEMICAL RESEARCH

Downregulation of Genes Involved in Metabolism and Oxidative Stress in the Peripheral Leukocytes of Huntington's Disease Patients

(2012) Kuo-Hsuan Chang et al.   PLoS One

PGC-1  Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function

(2012) T. Tsunemi et al.   Science Translational Medicine

Pathogenic Cellular Phenotypes are Germline Transmissible in a Transgenic Primate Model of Huntington's Disease

(2012) Kittiphong Putkhao et al.   STEM CELLS AND DEVELOPMENT

Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter

(2011) Elodie Martin et al.   HUMAN MOLECULAR GENETICS

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

Huntington's disease: a clinical review

(2011) Raymund A.C. Roos   Orphanet Journal of Rare Diseases

Reprogramming Huntington Monkey Skin Cells into Pluripotent Stem Cells

(2010) Anthony W.S. Chan et al.   Cellular Reprogramming

Spatiotemporally restricted regulation of generic motor neuron programs by miR-196-mediated repression of Hoxb8

(2010) Naisana S. Asli et al.   DEVELOPMENTAL BIOLOGY

Altered microRNA regulation in Huntington's disease models

(2010) Soon-Tae Lee et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

(2010) J. Kim et al.   HUMAN MOLECULAR GENETICS

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

(2010) Ming-Chang Chiang et al.   HUMAN MOLECULAR GENETICS

Diminished Activity-Dependent Brain-Derived Neurotrophic Factor Expression Underlies Cortical Neuron Microcircuit Hypoconnectivity Resulting from Exposure to Mutant Huntingtin Fragments

(2010) L. Gambazzi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events

(2009) Tina Sehm et al.   DEVELOPMENTAL BIOLOGY

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington's disease

(2009) Yun-Sik Choi et al.   NEUROBIOLOGY OF DISEASE

microRNAs in CNS Disorders

(2009) Jannet Kocerha et al.   NEUROMOLECULAR MEDICINE

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

(2009) J. Kocerha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards a transgenic model of Huntington’s disease in a non-human primate

(2008) Shang-Hsun Yang et al.   NATURE

MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers

(2008) R Luthra et al.   ONCOGENE

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA