Sustained Treatment with Insulin Detemir in Mice Alters Brain Activity and Locomotion

Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin

(2015) Denovan P. Begg et al.   DIABETES

Effect of subcutaneous insulin detemir on glucose flux and lipolysis during hyperglycaemia in people with type 1 diabetes

(2015) R. A. Herring et al.   DIABETES OBESITY & METABOLISM

Effects of Insulin Detemir and NPH Insulin on Body Weight and Appetite-Regulating Brain Regions in Human Type 1 Diabetes: A Randomized Controlled Trial

(2014) Larissa W. van Golen et al.   PLoS One

Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior

(2012) T. Sartorius et al.   DIABETES

Toll-like receptors 2 and 4 impair insulin-mediated brain activity by interleukin-6 and osteopontin and alter sleep architecture

(2012) Tina Sartorius et al.   FASEB JOURNAL

High cerebral insulin sensitivity is associated with loss of body fat during lifestyle intervention

(2011) O. Tschritter et al.   DIABETOLOGIA

Euglycemic Infusion of Insulin Detemir Compared With Human Insulin Appears to Increase Direct Current Brain Potential Response and Reduces Food Intake While Inducing Similar Systemic Effects

(2010) M. Hallschmid et al.   DIABETES

Insulin detemir causes increased symptom awareness during hypoglycaemia compared to human insulin

(2009) O. Tschritter et al.   DIABETES OBESITY & METABOLISM

Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity

(2009) A. M. Hennige et al.   DIABETOLOGIA

The Insulin Effect on Cerebrocortical Theta Activity Is Associated with Serum Concentrations of Saturated Nonesterified Fatty Acids

(2009) Otto Tschritter et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Activation of Stat3 Signaling in AgRP Neurons Promotes Locomotor Activity

(2008) Andrea Mesaros et al.   Cell Metabolism

A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes

(2008) J. Rosenstock et al.   DIABETOLOGIA