Testing the H56 Vaccine Delivered in 4 Different Adjuvants as a BCG-Booster in a Non-Human Primate Model of Tuberculosis

Interferon γ and Tumor Necrosis Factor Are Not Essential Parameters of CD4+T-Cell Responses for Vaccine Control of Tuberculosis

(2015) Mark T. Orr et al.   JOURNAL OF INFECTIOUS DISEASES

Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

(2015) Hannah Priyadarshini Gideon et al.   PLoS Pathogens

Monkey Models of Tuberculosis: Lessons Learned

(2014) Juliet C. Peña et al.   INFECTION AND IMMUNITY

A Simple Mycobacterial Monomycolated Glycerol Lipid Has Potent Immunostimulatory Activity

(2014) C. S. Andersen et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells

(2014) S. Sakai et al.   JOURNAL OF IMMUNOLOGY

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Tuberculosis vaccines – rethinking the current paradigm

(2014) Peter Andersen et al.   TRENDS IN IMMUNOLOGY

Novel Vaccination Strategies against Tuberculosis

(2014) P. Andersen et al.   Cold Spring Harbor Perspectives in Medicine

Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review

(2014) Stefan H E Kaufmann et al.   Lancet Respiratory Medicine

Control of Chronic Mycobacterium tuberculosis Infection by CD4 KLRG1- IL-2-Secreting Central Memory Cells

(2013) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

(2013) Yared Hailemichael et al.   NATURE MEDICINE

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

Comparing Adjuvanted H28 and Modified Vaccinia Virus Ankara Expressing H28 in a Mouse and a Non-Human Primate Tuberculosis Model

(2013) Rolf Billeskov et al.   PLoS One

ESAT-6 (EsxA) and TB10.4 (EsxH) Based Vaccines for Pre- and Post-Exposure Tuberculosis Vaccination

(2013) Truc Hoang et al.   PLoS One

Chlamydia muridarum T Cell Antigens and Adjuvants That Induce Protective Immunity in Mice

(2012) Hong Yu et al.   INFECTION AND IMMUNITY

The non-human primate model of tuberculosis

(2012) D. Kaushal et al.   JOURNAL OF MEDICAL PRIMATOLOGY

CAF05: cationic liposomes that incorporate synthetic cord factor and poly(I:C) induce CTL immunity and reduce tumor burden in mice

(2011) Jon Hansen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

(2011) Philana Ling Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

A multistage tuberculosis vaccine that confers efficient protection before and after exposure

(2011) Claus Aagaard et al.   NATURE MEDICINE

A Gamma Interferon Independent Mechanism of CD4 T Cell Mediated Control of M. tuberculosis Infection in vivo

(2011) Alena M. Gallegos et al.   PLoS Pathogens

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Establishment of an Aerosol Challenge Model of Tuberculosis in Rhesus Macaques and an Evaluation of Endpoints for Vaccine Testing

(2010) S. A. Sharpe et al.   Clinical and Vaccine Immunology

Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

(2010) Pernille Nordly et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Immunity by formulation design: Induction of high CD8+ T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method

(2010) Pernille Nordly et al.   JOURNAL OF CONTROLLED RELEASE

Viral Booster Vaccines Improve Mycobacterium bovis BCG-Induced Protection against Bovine Tuberculosis

(2009) H. M. Vordermeier et al.   INFECTION AND IMMUNITY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen

(2009) Malou Henriksen-Lacey et al.   JOURNAL OF CONTROLLED RELEASE

Novel Generation Mycobacterial Adjuvant Based on Liposome-Encapsulated Monomycoloyl Glycerol from Mycobacterium bovis Bacillus Calmette-Guerin

(2009) C. A. S. Andersen et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Protection and Polyfunctional T Cells Induced by Ag85B-TB10.4/IC31® against Mycobacterium tuberculosis Is Highly Dependent on the Antigen Dose

(2009) Claus Aagaard et al.   PLoS One

MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

(2009) Frank A. W. Verreck et al.   PLoS One