Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus

Enhanced Neutralizing Antibody Response Induced by Respiratory Syncytial Virus Prefusion F Protein Expressed by a Vaccine Candidate

(2015) Bo Liang et al.   JOURNAL OF VIROLOGY

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

(2015) Young Do Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

(2015) Guillaume B. E. Stewart-Jones et al.   PLoS One

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

(2015) A. Impagliazzo et al.   SCIENCE

Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

(2015) Joan O. Ngwuta et al.   Science Translational Medicine

Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections

(2015) Geraldine Taylor et al.   Science Translational Medicine

Evaluation of candidate vaccine approaches for MERS-CoV

(2015) Lingshu Wang et al.   Nature Communications

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

(2015) Anders Krarup et al.   Nature Communications

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

(2015) Young Do Kwon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

(2015) Morgan S. A. Gilman et al.   PLoS Pathogens

Plant Molecular Pharming for the Treatment of Chronic and Infectious Diseases

(2014) Eva Stoger et al.   Annual Review of Plant Biology

Sendai virus recombinant vaccine expressing a secreted, unconstrained respiratory syncytial virus fusion protein protects against RSV in cotton rats

(2014) Xiaoyan Zhan et al.   INTERNATIONAL IMMUNOLOGY

Recombinant protein subunit vaccine synthesis in microbes: a role for yeast?

(2014) Roslyn M. Bill   JOURNAL OF PHARMACY AND PHARMACOLOGY

Proof of principle for epitope-focused vaccine design

(2014) Bruno E. Correia et al.   NATURE

Generation of a universal CD4 memory T cell recall peptide effective in humans, mice and non-human primates

(2014) Christopher C. Fraser et al.   VACCINE

Label-free methods of reporting biomolecular interactions by optical biosensors

(2013) Marimuthu Citartan et al.   ANALYST

Respiratory Syncytial Virus—A Comprehensive Review

(2013) Andrea T. Borchers et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Recombinant protein production in bacterial hosts

(2013) Tim W. Overton   DRUG DISCOVERY TODAY

Genetic Vaccine for Respiratory Syncytial Virus Provides Protection Without Disease Potentiation

(2013) Teresa R Johnson et al.   MOLECULAR THERAPY

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

(2013) Davide Corti et al.   NATURE

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies

(2013) Masaru Kanekiyo et al.   NATURE

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Strategic priorities for respiratory syncytial virus (RSV) vaccine development

(2013) L.J. Anderson et al.   VACCINE

Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

(2012) Gale Smith et al.   PLoS One

A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis

(2012) Anne L. Hotard et al.   VIROLOGY

Improved expression of secretory and trimeric proteins in mammalian cells via the introduction of a new trimer motif and a mutant of the tPA signal sequence

(2011) Jia-Ye Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of recombinant proteins by yeast cells

(2011) Eda Çelik et al.   BIOTECHNOLOGY ADVANCES

Green factory: Plants as bioproduction platforms for recombinant proteins

(2011) Jianfeng Xu et al.   BIOTECHNOLOGY ADVANCES

Insect cell technology is a versatile and robust vaccine manufacturing platform

(2011) Jimmy A Mena et al.   Expert Review of Vaccines

Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus

(2011) Jason S. McLellan et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

(2011) Jason S. McLellan et al.   NATURE

Transgenic apple expressing an antigenic protein of the human respiratory syncytial virus

(2010) Joann M. Lau et al.   JOURNAL OF PLANT PHYSIOLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Structural basis of respiratory syncytial virus neutralization by motavizumab

(2010) Jason S McLellan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Poxvirus Proteomics and Virus-Host Protein Interactions

(2009) K. Van Vliet et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs

(2009) Tanvir R Shaikh et al.   Nature Protocols