Pharmacokinetic-Pharmacodynamic Analysis on Inflammation Rat Model after Oral Administration of Huang Lian Jie Du Decoction

Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma

(2015) Ning Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of Huang-Lian-Jie-Du-Tang decoction

(2014) Zhao-Tang Ma et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Comparative pharmacokinetic investigation on baicalin and wogonoside in type 2 diabetic and normal rats after oral administration of traditional Chinese medicine Huanglian Jiedu decoction

(2014) Meng-Yun He et al.   JOURNAL OF ETHNOPHARMACOLOGY

Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang

(2014) Huawei Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of Huanglian-Jie-Du-Tang and Its Modified Formula on the Modulation of Amyloid-β Precursor Protein Processing in Alzheimer's Disease Models

(2014) Siva Sundara Kumar Durairajan et al.   PLoS One

At the bench: the key role of PK-PD modelling in enabling the early discovery of biologic therapies

(2013) Mark Penney et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Bioinformatics Analysis for the Antirheumatic Effects of Huang-Lian-Jie-Du-Tang from a Network Perspective

(2013) Haiyang Fang et al.   Evidence-based Complementary and Alternative Medicine

Chemical profiling and quantification of Chinese medicinal formula Huang-Lian-Jie-Du decoction, a systematic quality control strategy using ultra high performance liquid chromatography combined with hybrid quadrupole-orbitrap and triple quadrupole mass spectrometers

(2013) Yang Yang et al.   JOURNAL OF CHROMATOGRAPHY A

Protective effects of Huang-Lian-Jie-Du-Tang and its component group on collagen-induced arthritis in rats

(2013) Yaohua Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotective effects of Huang-Lian-Jie-Du-Decoction on ischemic stroke rats revealed by 1H NMR metabolomics approach

(2013) Peng-Ran Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Novel pharmacokinetic studies of the Chinese formula Huang-Lian-Jie-Du-Tang in MCAO rats

(2013) Huaxu Zhu et al.   PHYTOMEDICINE

Hypolipidemic effect of the Chinese polyherbal Huanglian Jiedu decoction in type 2 diabetic rats and its possible mechanism

(2013) Xiao-Jie Zhang et al.   PHYTOMEDICINE

Huang-Lian-Jie-Du-Tang Protects Rats from Cardiac Damages Induced by Metabolic Disorder by Improving Inflammation-Mediated Insulin Resistance

(2013) Chuan Bao Li et al.   PLoS One

Therapeutic effects of a novel tylophorine analog, NK-007, on collagen-induced arthritis through suppressing tumor necrosis factor α production and Th17 cell differentiation

(2012) Ti Wen et al.   ARTHRITIS AND RHEUMATISM

Protection of Long-Term Treatment With Huang-Lian-Jie-Du-Tang on Vascular Endothelium in Rats With Type 2 Diabetes Mellitus

(2012) Quan Yi et al.   CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL

Comparative pharmacokinetics of baicalin in normal and the type 2 diabetic rats after oral administration of the Radix scutellariae extract

(2012) Yuan-Xiong Deng et al.   FITOTERAPIA

Integrated pharmacokinetics of major bioactive components in MCAO rats after oral administration of Huang-Lian-Jie-Du-Tang

(2012) Huaxu Zhu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Rapid-resolution liquid chromatography TOF-MS for urine metabolomic analysis of collagen-induced arthritis in rats and its applications

(2012) Rongcai Yue et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of Intestinal First-Pass Hydrolysis on the Oral Bioavailability of an Ester Prodrug of Fexofenadine

(2012) Kayoko Ohura et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway

(2011) Huawu Zeng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-inflammatory effects of Huang-Lian-Jie-Du decoction, its two fractions and four typical compounds

(2011) Juan Lu et al.   JOURNAL OF ETHNOPHARMACOLOGY

In vivo and in vitro inhibitory effects of a traditional Chinese formulation on LPS-stimulated leukocyte–endothelial cell adhesion and VCAM-1 gene expression

(2011) Yi-Hong Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Comparative pharmacokinetics of baicalin in plasma after oral administration of Huang-Lian-Jie-Du-Tang or pure baicalin in MCAO and sham-operated rats

(2010) Ming-fei Zeng et al.   FITOTERAPIA

Huang-Lian-Jie-Du-Tang exerts anti-inflammatory effects in rats through inhibition of nitric oxide production and eicosanoid biosynthesis via the lipoxygenase pathway

(2010) Huawu Zeng et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Contribution of a significant first-pass effect of dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylene dioxybiphenyl-2,2′-dicarboxylate in the liver to its poor bioavailability in rats

(2010) Kyung-Ha Yu et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Increased Oral AUC of Baicalin in Streptozotocin-Induced Diabetic Rats due to the Increased Activity of Intestinal β-Glucuronidase

(2009) Li Liu et al.   PLANTA MEDICA

Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect

(2009) H. E. Kang et al.   XENOBIOTICA

Adverse functions of IL-17A in experimental sepsis

(2008) Michael A. Flierl et al.   FASEB JOURNAL

Simultaneous determination of 24 sulfonamide residues in meat by ultra-performance liquid chromatography tandem mass spectrometry

(2008) Zengxuan Cai et al.   JOURNAL OF CHROMATOGRAPHY A

Simultaneous determination of berberine, palmatine and jatrorrhizine by liquid chromatography–tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of coptis–evodia herb couple

(2008) Yating Deng et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect

(2008) Soo K. Bae et al.   JOURNAL OF PHARMACEUTICAL SCIENCES