Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice

Pharmacological treatment of idiopathic pulmonary fibrosis: an update

(2015) Paolo Spagnolo et al.   DRUG DISCOVERY TODAY

Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury

(2014) Yedidya Saiman et al.   HEPATOLOGY RESEARCH

Retraction: Dual Effect of AMD3100, a CXCR4 Antagonist, on Bleomycin-Indiced Lung Inflammation

(2014) M. Watanabe et al.   JOURNAL OF IMMUNOLOGY

Fibrocytes Are Not an Essential Source of Type I Collagen during Lung Fibrosis

(2014) Kathryn R. Kleaveland et al.   JOURNAL OF IMMUNOLOGY

Idiopathic pulmonary fibrosis in US Medicare beneficiaries aged 65 years and older: incidence, prevalence, and survival, 2001–11

(2014) Ganesh Raghu et al.   Lancet Respiratory Medicine

Role of Lung Pericytes and Resident Fibroblasts in the Pathogenesis of Pulmonary Fibrosis

(2013) Chi Hung et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

(2013) Bi-Sen Ding et al.   NATURE

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Small Molecule Inhibitors of CXCR4

(2013) Bikash Debnath et al.   Theranostics

Liver fibrosis: a bidirectional model of fibrogenesis and resolution

(2012) P. Ramachandran et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

The molecular pharmacology of AMD11070: An orally bioavailable CXCR4 HIV entry inhibitor

(2011) Renee M. Mosi et al.   BIOCHEMICAL PHARMACOLOGY

Genetic deletion of Cyp26b1 negatively impacts limb skeletogenesis by inhibiting chondrogenesis

(2011) H. J. Dranse et al.   JOURNAL OF CELL SCIENCE

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials

(2011) Paul W Noble et al.   LANCET

Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis

(2010) Jeong Sup Song et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication

(2010) Renato T. Skerlj et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chronic Alcohol Intake Interferes with Retinoid Metabolism and Signaling

(2010) Xiang-Dong Wang   NUTRITION REVIEWS

Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis

(2009) Antje Moeller et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hepatic stellate cells express functional CXCR4: Role in stromal cell-derived factor-1α-mediated stellate cell activation

(2009) Feng Hong et al.   HEPATOLOGY

Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers

(2008) Y. J. Cao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Global Impact of Hepatic Fibrosis and End-Stage Liver Disease

(2008) Young-Suk Lim et al.   Clinics in Liver Disease

AMD070, a CXCR4 Chemokine Receptor Antagonist: Practical Large-Scale Laboratory Synthesis

(2008) Jason B. Crawford et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT