Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1

Interleukin 1 Type 1 Receptor Restore: A Genetic Mouse Model for Studying Interleukin 1 Receptor-Mediated Effects in Specific Cell Types

(2015) X. Liu et al.   JOURNAL OF NEUROSCIENCE

Interleukin 1β

(2014) Stephanie McCarty et al.   Cardiology in Review

CYTOKINE TARGETS IN THE BRAIN: IMPACT ON NEUROTRANSMITTERS AND NEUROCIRCUITS

(2013) Andrew H. Miller et al.   DEPRESSION AND ANXIETY

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions

(2013) Praxedis Martin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1β

(2013) Sarah C. Hopp et al.   JOURNAL OF NEUROIMMUNOLOGY

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

Genetic targeting of the amphetamine and methylphenidate-sensitive dopamine transporter: On the path to an animal model of attention-deficit hyperactivity disorder

(2013) Marc A. Mergy et al.   NEUROCHEMISTRY INTERNATIONAL

Treating inflammation by blocking interleukin-1 in humans

(2013) Charles A. Dinarello et al.   SEMINARS IN IMMUNOLOGY

Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes

(2012) Helen E. Thomas et al.   Annals of the New York Academy of Sciences

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Interleukin-1R3 mediates interleukin-1–induced potassium current increase through fast activation of Akt kinase

(2012) Jiang Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice

(2011) Shay Shemesh et al.   ATHEROSCLEROSIS

Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice

(2011) Matthew R. Alexander et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1 Receptor Activation by Systemic Lipopolysaccharide Induces Behavioral Despair Linked to MAPK Regulation of CNS Serotonin Transporters

(2010) Chong-Bin Zhu et al.   NEUROPSYCHOPHARMACOLOGY

Expression and Function of TNF and IL-1 Receptors on Human Regulatory T Cells

(2010) Frances Mercer et al.   PLoS One

Three Promoters Regulate Tissue- and Cell Type-specific Expression of Murine Interleukin-1 Receptor Type I

(2009) Qun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleen

(2007) Harald Engler et al.   PSYCHONEUROENDOCRINOLOGY