The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells
Authors
Keywords
Autophagic cell death, Mitochondria, Apoptosis, Cell metabolism, Small interfering RNAs, Endoplasmic reticulum, Stress signaling cascade, Fluorescence microscopy
Journal
PLoS One
Volume 11, Issue 2, Pages e0148999
Publisher
Public Library of Science (PLoS)
Online
2016-02-06
DOI
10.1371/journal.pone.0148999
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming
- (2015) Yasong Wu et al. NATURE CELL BIOLOGY
- MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
- (2015) Remi-Martin Laberge et al. NATURE CELL BIOLOGY
- UPR, autophagy, and mitochondria crosstalk underlies the ER stress response
- (2015) Daniela Senft et al. TRENDS IN BIOCHEMICAL SCIENCES
- Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis
- (2015) Jing Xue et al. Nature Communications
- Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: The protective role of autophagy in apoptosis
- (2014) Kyoung-Sub Song et al. Autophagy
- Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
- (2014) Tania Valencia et al. CANCER CELL
- Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival
- (2014) Berna C. Özdemir et al. CANCER CELL
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- The role of the hepatocyte growth factor/c-MET pathway in pancreatic stellate cell–endothelial cell interactions: antiangiogenic implications in pancreatic cancer
- (2014) Mishaal B. Patel et al. CARCINOGENESIS
- To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
- (2014) Douglas R. Green et al. CELL
- Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation
- (2014) Wafa B'chir et al. CELLULAR SIGNALLING
- Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells
- (2014) Wenyan Lu et al. CELLULAR SIGNALLING
- Targeting c-MET/HGF Signaling Pathway in Upper Gastrointestinal Cancers: Rationale and Progress
- (2014) Sharareh Gholamin et al. CURRENT DRUG TARGETS
- Mitochondrial dynamics and inheritance during cell division, development and disease
- (2014) Prashant Mishra et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells
- (2014) Ming Ming et al. PLoS One
- Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
- (2014) M. Lu et al. SCIENCE
- MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond
- (2013) Jean E. Vance BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
- (2013) Dhruv Kumar et al. CANCER LETTERS
- A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment
- (2013) Minoti V. Apte et al. GASTROENTEROLOGY
- Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy
- (2013) Virginia Hernández-Gea et al. JOURNAL OF HEPATOLOGY
- Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms
- (2013) Dhruv Kumar et al. Molecular Cancer
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
- (2013) Wafa B’chir et al. NUCLEIC ACIDS RESEARCH
- Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells
- (2013) Heloisa P. Soares et al. PLoS One
- Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues
- (2012) Virginia Hernández–Gea et al. GASTROENTEROLOGY
- Epidemiology, risk factors, and the promotion of pancreatic cancer: Role of the stellate cell
- (2012) Stephen Pandol et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Post-transcriptional regulation of VEGF-A mRNA levels by mitogen-activated protein kinases (MAPKs) during metabolic stress associated with ischaemia/reperfusion
- (2012) Bryan W. Miller et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- AMPK: a nutrient and energy sensor that maintains energy homeostasis
- (2012) D. Grahame Hardie et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Rottlerin and Cancer: Novel Evidence and Mechanisms
- (2012) E. Maioli et al. TheScientificWorldJOURNAL
- Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
- (2012) Christian Appenzeller-Herzog et al. TRENDS IN CELL BIOLOGY
- Metabolic Stress in Autophagy and Cell Death Pathways
- (2012) B. J. Altman et al. Cold Spring Harbor Perspectives in Biology
- Thyroid hormone differentially modulates Warburg phenotype in breast cancer cells
- (2011) Sonal Suhane et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to EnhanceCHOPTranslation
- (2011) Lakshmi Reddy Palam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteomic Analysis of an Immortalized Mouse Pancreatic Stellate Cell Line Identifies Differentially-Expressed Proteins in Activated vs Nonproliferating Cell States
- (2011) Joao A. Paulo et al. JOURNAL OF PROTEOME RESEARCH
- The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
- (2011) Maria M. Mihaylova et al. NATURE CELL BIOLOGY
- Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner
- (2010) Adem Kalender et al. Cell Metabolism
- Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression
- (2010) Jane C. Goodall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family
- (2009) Izumi Ohno et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- In search of an “autophagomometer”
- (2009) David C. Rubinsztein et al. Autophagy
- Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose Deprivation
- (2009) S. Saito et al. CANCER RESEARCH
- Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-δ-independent pathway in human colon cancer cells
- (2008) Jun Hee Lim et al. APOPTOSIS
- Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues
- (2008) Kanou Kojima et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial dynamics and apoptosis
- (2008) D.-F. Suen et al. GENES & DEVELOPMENT
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search