Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study

Motor function measure scale, steroid therapy and patients with Duchenne muscular dystrophy

(2017) Elaine C. da Silva et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia

(2016) Derek T. Hall et al.   Aging-US

Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free l-arginine in humans

(2015) Arslan Arinc Kayacelebi et al.   AMINO ACIDS

The l-arginine/NO pathway and homoarginine are altered in Duchenne muscular dystrophy and improved by glucocorticoids

(2015) Irina Hörster et al.   AMINO ACIDS

Differential associations of circulating asymmetric dimethylarginine and cell adhesion molecules with metformin use in patients with type 2 diabetes mellitus and stable coronary artery disease

(2015) Olga Kruszelnicka et al.   AMINO ACIDS

Metformin increases peroxisome proliferator-activated receptor γ Co-activator-1α and utrophin a expression in dystrophic skeletal muscle

(2015) Vladimir Ljubicic et al.   MUSCLE & NERVE

Quantitative muscle MRI: A powerful surrogate outcome measure in Duchenne muscular dystrophy

(2015) Ulrike Bonati et al.   NEUROMUSCULAR DISORDERS

Dystrophin–glycoprotein complex regulates muscle nitric oxide production through mechanoregulation of AMPK signaling

(2015) Joanne F. Garbincius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy

(2014) Nanna Witting et al.   ANNALS OF NEUROLOGY

Dystropathology Increases Energy Expenditure and Protein Turnover in the Mdx Mouse Model of Duchenne Muscular Dystrophy

(2014) Hannah G. Radley-Crabb et al.   PLoS One

Metformin Protects Skeletal Muscle from Cardiotoxin Induced Degeneration

(2014) Francesca Langone et al.   PLoS One

Skeletal Muscle Function during Exercise—Fine-Tuning of Diverse Subsystems by Nitric Oxide

(2013) Frank Suhr et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Magnetic resonance imaging in duchenne muscular dystrophy: Longitudinal assessment of natural history over 18 months

(2013) Kieren G. Hollingsworth et al.   MUSCLE & NERVE

Ibuprofen plus isosorbide dinitrate treatment in the mdx mice ameliorates dystrophic heart structure

(2013) Clara Sciorati et al.   PHARMACOLOGICAL RESEARCH

AMPK Activation Stimulates Autophagy and Ameliorates Muscular Dystrophy in the mdx Mouse Diaphragm

(2012) Marion Pauly et al.   AMERICAN JOURNAL OF PATHOLOGY

Predicting resting energy expenditure in boys with Duchenne muscular dystrophy

(2012) Sarah A. Elliott et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Quantitative MRI and loss of free ambulation in Duchenne muscular dystrophy

(2012) Arne Fischmann et al.   JOURNAL OF NEUROLOGY

L-Arginine enhances glucose and lipid metabolism in rat L6 myotubes via the NO/ c-GMP pathway

(2012) Thais de Castro Barbosa et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy

(2012) Naoki Ito et al.   NATURE MEDICINE

Nitric oxide donor and non steroidal anti inflammatory drugs as a therapy for muscular dystrophies: Evidence from a safety study with pilot efficacy measures in adult dystrophic patients

(2012) Maria Grazia D’Angelo et al.   PHARMACOLOGICAL RESEARCH

Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model

(2012) Vanessa E Jahnke et al.   Skeletal Muscle

Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle

(2011) V. Ljubicic et al.   HUMAN MOLECULAR GENETICS

Functional changes in Duchenne muscular dystrophy: A 12-month longitudinal cohort study

(2011) E. Mazzone et al.   NEUROLOGY

Muscle fat-fraction and mapping in Duchenne muscular dystrophy: evaluation of disease distribution and correlation with clinical assessments

(2011) Michele Gaeta et al.   SKELETAL RADIOLOGY

The ADMA-Metformin Hypothesis: Linking the Cardiovascular Consequences of the Metabolic Syndrome and Type 2 Diabetes

(2011) William H. Bestermann et al.   CardioRenal Medicine

AMPK-mediated regulation of transcription in skeletal muscle

(2010) Sean L. McGee et al.   CLINICAL SCIENCE

Metformin Activates AMP Kinase through Inhibition of AMP Deaminase

(2010) Jiangyong Ouyang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monitoring changes and predicting loss of ambulation in Duchenne muscular dystrophy with the Motor Function Measure

(2009) CAROLE VUILLEROT et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Skeletal Muscle AMP-activated Protein Kinase Is Essential for the Metabolic Response to Exercisein Vivo

(2009) Robert S. Lee-Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of regional body composition with dual-energy X-ray absorptiometry in Duchenne muscular dystrophy: Correlation of regional lean mass and quantitative strength

(2009) Andrew J. Skalsky et al.   MUSCLE & NERVE

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE