Article
Endocrinology & Metabolism
Bo Song, Cihang Lu, Di Teng, Zhongyan Shan, Weiping Teng
Summary: This study investigates the correlation between different metabolic phenotypes of obesity and thyroid disorders. It found that metabolically unhealthy individuals, both with and without obesity, have a higher risk of thyroid disorders than metabolically healthy individuals without obesity.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Xiaoru Qin, Chaolei Chen, Jiabin Wang, Anping Cai, Xiaoxuan Feng, Xiaofei Jiang, Yingqing Feng
Summary: This study investigated the associations between various adiposity indices and cardiometabolic multimorbidity (CMM) among Chinese adults. The findings suggest that waist circumference and waist-to-height ratio are more strongly associated with CMM compared to body mass index. These indices also have better discriminative ability for CMM compared to BMI.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Environmental Sciences
Chao Yang, Wanzhou Wang, Ze Liang, Yueyao Wang, Rui Chen, Chenyu Liang, Fulin Wang, Pengfei Li, Lin Ma, Feili Wei, Shuangcheng Li, Luxia Zhang
Summary: Based on a nationwide survey, this study evaluated the associations between fine particulate matter (PM2.5) and nitrogen dioxide (NO2) concentrations with the prevalence of obesity and abdominal obesity. The results showed that increased levels of PM2.5 and NO2 were associated with higher prevalence of obesity and abdominal obesity. People in rural regions experienced stronger adverse effects than those in urban regions, and lower night light index values amplified the associations of PM2.5 and NO2 with obesity and abdominal obesity.
ENVIRONMENTAL POLLUTION
(2023)
Article
Immunology
Chunchun Yuan, Jing Wang, Weiqiang Zhang, Honggang Yi, Bing Shu, Chenguang Li, Qianqian Liang, De Liang, Bolai Chen, Xingwen Xie, Xinchao Lin, Xu Wei, Hui Wang, Peizhan Chen, Chen Huang, Hao Xu, Yueli Sun, Yongjian Zhao, Qi Shi, Dezhi Tang, Yongjun Wang
Summary: This study investigated the effects of lower 25(OH)D levels in obesity on bone health in elderly Chinese people. The results showed that obese individuals had lower 25(OH)D levels and higher bone mineral density (BMD) compared to normal individuals. The study revealed that BMI and 25(OH)D levels were positively associated with BMD outcomes.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Environmental Sciences
Suzhen Cao, Qian Guo, Tao Xue, Beibei Wang, Limin Wang, Xiaoli Duan, Junfeng (Jim) Zhang
Summary: This study found that long-term exposure to ambient PM2.5 may increase the risk of obesity in Chinese adults, especially in individuals of older age, Han ethnicity, lower socioeconomic status, and unfavorable dietary and living conditions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Endocrinology & Metabolism
Lisa Kakinami, Prince Kevin Danieles, Kehinde Ajibade, Sylvia Santosa, Jessica Murphy
Summary: Analysis of NHANES data revealed that classifying adiposity based on DXA muscle and fat mass phenotypes was less accurate in predicting cardiometabolic risk compared to BMI weight status.
Article
Public, Environmental & Occupational Health
Wanyue Dong, Zhonghe Sun, Ruhai Bai
Summary: This study identified the prevalence of nutritional supplement (NS) use among older Chinese adults and found that factors such as gender, age, urban residence, higher education, better living conditions, and lifestyle habits were associated with NS use.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Nazlisadat Seyed Khoei, Karl-Heinz Wagner, Anja M. Sedlmeier, Marc J. Gunter, Neil Murphy, Heinz Freisling
Summary: There is an inverse association between bilirubin levels and cardiometabolic risk factors including adiposity, dyslipidemia, and hypertension.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Psychology, Multidisciplinary
Min An, Xiao Zhang, Ying Wang, Jingxin Zhao
Summary: This study tested the longitudinal measurement invariance of Elliot and McGregor's (2001) achievement goal scale and examined the growth trajectories of emerging adults' achievement goals over time. The results showed that the achievement goal scale demonstrated longitudinal measurement invariance. The findings also revealed an overall decline in three types of achievement goals over time, with individual variability in initial levels and growth rates.
CURRENT PSYCHOLOGY
(2022)
Article
Nutrition & Dietetics
Junjie Zhu, Yue Zhang, Yiling Wu, Yu Xiang, Xin Tong, Yuting Yu, Yun Qiu, Shuheng Cui, Qi Zhao, Na Wang, Yonggen Jiang, Genming Zhao
Summary: This study examined the association between obesity and dyslipidemia among Chinese adults in Shanghai. The study found that participants with obesity had a higher risk of high cholesterol, high triglycerides, high LDL-C, and low HDL-C. Gender, age, hypertension, and diabetes were found to potentially modify this association.
Article
Psychology, Multidisciplinary
Yanhua Zhao
Summary: This study investigates the predictive effects of different social achievement goals on social anxiety and depression symptoms in university students, and suggests that self-esteem may serve as a mediator in this relationship. The findings indicate that pursuing social mastery goals and performance-approach goals enhances students' self-esteem and reduces their social anxiety and depression symptoms, while striving to avoid negative evaluation in social contexts is associated with lower self-esteem and increased social anxiety and depression symptoms.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Allergy
Xiao Zhang, Mei Zhang, Haijing Sui, Chun Li, Zhengjing Huang, Bo Liu, Xiaoting Song, Shuanglu Liao, Miao Yu, Tingting Luan, Torsten Zuberbier, Limin Wang, Zuotao Zhao, Jing Wu
Summary: Allergic rhinitis is prevalent among Chinese adults, and the associated factors and interactions are helpful for designing targeted prevention strategies. However, available evidence on the prevalence of allergic rhinitis among Chinese adults is limited.
WORLD ALLERGY ORGANIZATION JOURNAL
(2023)
Article
Public, Environmental & Occupational Health
Katherine Y. P. Sze, Eric K. P. Lee, Rufina H. W. Chan, Jean H. Kim
Summary: This study found that negative emotional eating is prevalent among female Chinese university students and not uncommon among male students. Management of negative emotional eating should be included as a component of university mental health promotion programmes in the region.
Article
Multidisciplinary Sciences
Moynul Hasan, Sumaya Sultana, Md. Sohan, Shahnaj Parvin, Md. Ashrafur Rahman, Md. Jamal Hossain, Mohammad Saydur Rahman, Md. Rabiul Islam
Summary: The prevalence of mental health disorders, such as loneliness, generalized anxiety disorder, and depressive disorder, is high among women with PCOS in Bangladesh. Various factors, including obesity, financial condition, physical exercise, mealtime, food habit, daily water consumption, birth control method, and long-term oral contraceptive pills, contribute to the development of mental health disorders among females with PCOS in Bangladesh.
Article
Critical Care Medicine
Jing Wang, Bo Hu, Zhiyong Peng, Huimin Song, Shuhan Cai, Xin Rao, Lu Li, Jianguo Li
Summary: This study investigated the prevalence of burnout in ICU physicians in mainland China, finding that high rates of burnout were associated with difficulty in treatment decisions, number of children, and income satisfaction. This highlights the importance of addressing these factors to prevent burnout in critical care physicians.
Review
Chemistry, Multidisciplinary
Fan-Shun Zhang, Qing-Ze He, Chengxue Helena Qin, Peter J. Little, Jian-Ping Weng, Suo-Wen Xu
Summary: Colchicine is an ancient herbal drug with unique anti-inflammatory effects and prominent cardiovascular actions. Clinical trials have confirmed its curative effect in treating cardiovascular diseases, and its anti-inflammatory mechanisms have been studied.
ACTA PHARMACOLOGICA SINICA
(2022)
Editorial Material
Endocrinology & Metabolism
Jianping Weng, Zhiguang Zhou, Lixin Guo
Article
Pharmacology & Pharmacy
Xiumei Wu, Mengyun Xu, Zhenghong Liu, Zhidan Zhang, Yujie Liu, Sihui Luo, Xueying Zheng, Peter J. Little, Suowen Xu, Jianping Weng
Summary: This study found that dual inhibition of IRAK1 and IRAK4 can effectively attenuate endothelial inflammation, lower LDL-C levels, and reduce atherosclerosis lesions. The findings support the importance of anti-inflammatory therapies in the treatment of cardiovascular diseases.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Joseph T. Wu, Shujiang Mei, Sihui Luo, Kathy Leung, Di Liu, Qiuying Lv, Jian Liu, Yuan Li, Kiesha Prem, Mark Jit, Jianping Weng, Tiejian Feng, Xueying Zheng, Gabriel M. Leung
Summary: Prolonged school closure has been widely implemented worldwide to control COVID-19, but research from China suggests that school children have a lower susceptibility to the virus compared to adults and the elderly. Using surveillance data and transmission models, it was found that school closures were less effective in reducing COVID-19 transmission due to the lower infection risk among school children. These findings, along with evidence of milder COVID-19 symptoms in children, suggest that long-term school closure may not be the ideal primary intervention for controlling the pandemic.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2022)
Article
Endocrinology & Metabolism
Sihui Luo, Xingwu Ran, Mei Zhang, Ji Hu, Daizhi Yang, Dalong Zhu, Jiajun Zhao, Xinhua Xiao, Xiaohui Guo, Tao Yang, Qin Huang, Fang Liu, Lu Jing, Jing Ma, Xinli Zhou, Fan Ping, Nan Gu, Wenwen Li, Yaling Yang, Chen Fang, Wei Bao, Xueying Zheng, Jinhua Yan, Zhiguang Zhou, Jianping Weng
Summary: Pregnancy outcomes of women with type 1 diabetes in China from 2004 to 2014 remained poor, showing higher rates of maternal mortality, pregnancy loss, preeclampsia, neonatal death, and congenital malformations compared to those without T1D. No significant improvement in outcomes was observed over this 11-year period.
JOURNAL OF DIABETES
(2022)
Article
Endocrinology & Metabolism
Qianwen Huang, Daizhi Yang, Hongrong Deng, Hua Liang, Xueying Zheng, Jinhua Yan, Wen Xu, Xiangwen Liu, Bin Yao, Sihui Luo, Jianping Weng
Summary: This study investigated the prevalence of MetS among adult patients with T1DM in China and found that patients with MetS were more likely to have DKD and DR. Female gender, longer diabetes duration, higher body mass index, and higher HbA1c were identified as risk factors associated with MetS.
DIABETES & METABOLISM JOURNAL
(2022)
Article
Endocrinology & Metabolism
Junxian Li, Lei Xu, Weijing Zhao, Jiemin Pan, Junxi Lu, Huijuan Lu, Jinhua Yan, Jianping Weng, Fang Liu
Summary: This study found that increased serum IL-17A is a risk factor for autoimmune type 1 diabetes (T1D) in Chinese population, while IL-17F is not independently associated with T1D. The GG genotype of IL17RA rs4819554 may decrease the risk of autoimmune T1D.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2022)
Review
Biochemistry & Molecular Biology
Meiming Su, Wenqi Zhao, Suowen Xu, Jianping Weng
Summary: Diabetes mellitus (DM) is a common chronic disease with significant complications. Resveratrol, a plant-derived compound, has shown protective effects against diabetes and its cardiovascular complications. These effects are mediated through various signaling pathways.
Review
Chemistry, Multidisciplinary
Suo-wen Xu, Iqra Ilyas, Jian-ping Weng
Summary: This review examines the impact of COVID-19 on endothelial cell function and provides a comprehensive summary of biomarkers associated with endothelial cell activation in COVID-19. COVID-19 is considered a vascular and endothelial disease, and several drugs have shown potential in improving clinical manifestations of patients. Further research using cellular and animal models can accelerate the discovery of new drugs targeting endothelial dysfunction in COVID-19 patients.
ACTA PHARMACOLOGICA SINICA
(2023)
Article
Nutrition & Dietetics
Meiming Su, Wenqi Zhao, Yujie Li, Hong Li, Suowen Xu, Jianping Weng
Summary: Atherosclerosis is a chronic inflammatory vascular disease in which endothelial cells play a crucial role. Resveratrol, a polyphenol, prevents cardiovascular disease by regulating multiple signaling pathways. The study suggests that resveratrol may serve as a shear stress mimetic drug for combating atherosclerosis.
Article
Biochemistry & Molecular Biology
Tong Yue, Huiling Tan, Yu Shi, Mengyun Xu, Sihui Luo, Jianping Weng, Suowen Xu
Summary: This study investigated the changes in metabolism during aging using machine learning and identified biomarkers associated with aging. The findings provide insights into potential therapeutic targets for delaying the effects of aging.
Article
Endocrinology & Metabolism
Yongwen Zhou, Mao Zheng, Hongrong Deng, Xueying Zheng, Sihui Luo, Daizhi Yang, Xiaodong Mai, Wen Xu, Jinhua Yan, Jianping Weng
Summary: This study aimed to capture glycemic fluctuation patterns and quantify contributions of basal and postprandial glucose increment to HbA1c levels among adults with type 1 diabetes. The results showed that basal hyperglycemia better predicts overall glycemic control than postprandial hyperglycemia. The relative contribution of basal hyperglycemia increased gradually with HbA1c increasing, and the strategy for insulin titration among type 1 diabetes patients varies with different levels of glycemic control.
JOURNAL OF DIABETES
(2023)
Article
Endocrinology & Metabolism
Ping Ling, Daizhi Yang, Chaofan Wang, Xueying Zheng, Sihui Luo, Xubin Yang, Hongrong Deng, Wen Xu, Jinhua Yan, Jianping Weng
Summary: This study aimed to derive a best-fitting model to calculate glucose management indicator (GMI) from mean blood glucose (MBG) obtained from continuous glucose monitoring (CGM) among pregnant women with type 1 diabetes mellitus (T1DM). After analyzing the CGM data and HbA1c levels of 98 pregnant women with T1DM, a pregnancy-specific GMI-MBG equation was developed. This equation should be recommended for antenatal clinical care.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Article
Multidisciplinary Sciences
Xuhong Hou, Limin Wang, Dalong Zhu, Lixin Guo, Jianping Weng, Mei Zhang, Zhiguang Zhou, Dajin Zou, Qiuhe Ji, Xiaohui Guo, Qiang Wu, Siyu Chen, Rong Yu, Hongli Chen, Zhengjing Huang, Xiao Zhang, Jiarui Wu, Jing Wu, Weiping Jia
Summary: The current epidemic status of diabetic retinopathy in China is unclear. A national survey was conducted to determine the prevalence and associated factors of diabetic retinopathy. The results showed a prevalence rate of 16.3% for diabetic retinopathy and 3.2% for vision-threatening diabetic retinopathy, with significant regional differences.
NATURE COMMUNICATIONS
(2023)
Review
Biochemistry & Molecular Biology
Xiumei Wu, Mengyun Xu, Mengya Geng, Shuo Chen, Peter J. Little, Suowen Xu, Jianping Weng
Summary: The increasing prevalence of noncommunicable diseases (NCDs) has become a significant global public health burden. Metabolic diseases, the most common form of NCDs, have life-threatening cardiovascular complications and affect people of all ages. Protein posttranslational modification (PTM) greatly enhances the functional diversity of proteins and plays a crucial role in common metabolic diseases such as diabetes, obesity, and fatty liver diseases. Understanding the mechanisms of PTMs in metabolic diseases will provide new insights for therapeutic intervention and improvement of therapies.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2023)