Novel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms

Visualization of the spatial and temporal dynamics of MAPK signaling using fluorescence imaging techniques

(2014) Taichiro Tomida   Journal of Physiological Sciences

Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

(2014) S. Ahmed et al.   Molecular Systems Biology

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Light-Mediated Kinetic Control Reveals the Temporal Effect of the Raf/MEK/ERK Pathway in PC12 Cell Neurite Outgrowth

(2014) Kai Zhang et al.   PLoS One

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Protein Coexpression Using FMDV 2A: Effect of “Linker” Residues

(2013) Ekaterina Minskaia et al.   Biomed Research International

The Temporal Pattern of Stimulation Determines the Extent and Duration of MAPK Activation in a Caenorhabditis elegans Sensory Neuron

(2012) T. Tomida et al.   Science Signaling

The secret life of kinases: functions beyond catalysis

(2011) Jens Rauch et al.   Cell Communication and Signaling

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Quantitative Co-Expression of Proteins at the Single Cell Level – Application to a Multimeric FRET Sensor

(2011) Joachim Goedhart et al.   PLoS One

Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear localization is dependent on docking domain interactions

(2010) C. J. Caunt et al.   JOURNAL OF CELL SCIENCE

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Mammalian MAPK/ERK Pathway Exhibits Properties of a Negative Feedback Amplifier

(2010) O. E. Sturm et al.   Science Signaling

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Noncatalytic Function of ERK1/2 Can Promote Raf/MEK/ERK-mediated Growth Arrest Signaling

(2009) Seung-Keun Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK Nuclear Translocation Is Dimerization-independent but Controlled by the Rate of Phosphorylation

(2009) Diane S. Lidke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Faithful Expression of Multiple Proteins via 2A-Peptide Self-Processing: A Versatile and Reliable Method for Manipulating Brain Circuits

(2009) W. Tang et al.   JOURNAL OF NEUROSCIENCE

The subcellular localization of MEK and ERK—A novel nuclear translocation signal (NTS) paves a way to the nucleus

(2009) Eldar Zehorai et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Dynamics and Variability of ERK2 Response to EGF in Individual Living Cells

(2009) Cellina Cohen-Saidon et al.   MOLECULAR CELL

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

(2009) Harish Shankaran et al.   Molecular Systems Biology

Use of the viral 2A peptide for bicistronic expression in transgenic mice

(2008) Georgios Trichas et al.   BMC BIOLOGY

Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation

(2008) S.F. Gabby Krens et al.   DEVELOPMENTAL BIOLOGY

Spatiotemporal Regulation of ERK2 by Dual Specificity Phosphatases

(2008) Christopher J. Caunt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Structural and FunctionalO-LinkedN-Acetylglucosamine-bearing Proteins inXenopus laevisOocyte

(2008) Vanessa Dehennaut et al.   MOLECULAR & CELLULAR PROTEOMICS