Inhibition on Proteasome β1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells

Inhibition of AKT/FoxO3a signaling induced PUMA expression in response to p53-independent cytotoxic effects of H1: A derivative of tetrandrine

(2015) Yin-Xu Zhang et al.   CANCER BIOLOGY & THERAPY

Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells

(2015) Ting Liu et al.   Oncotarget

Tetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen species

(2015) Haiqing Wang et al.   Cell and Bioscience

Induction of formation and conformational conversion of DNA G-quadruplexes by fangchinoline

(2014) Wei Tan et al.   Analytical Methods

Fangchinoline Inhibits Cell Proliferation Via Akt/GSK-3beta/cyclin D1 Signaling and Induces Apoptosis in MDA-MB-231 Breast Cancer Cells

(2014) Chang-Dong Wang et al.   Asian Pacific Journal of Cancer Prevention

Crosstalk between autophagy and proteasome protein degradation systems: possible implications for cancer therapy

(2014) Slawomir Wojcik   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

The clinical effectiveness and cost-effectiveness of bortezomib and thalidomide in combination regimens with an alkylating agent and a corticosteroid for the first-line treatment of multiple myeloma: a systematic review and economic evaluation.

(2014) J Picot et al.   HEALTH TECHNOLOGY ASSESSMENT

Emerging therapies targeting the ubiquitin proteasome system in cancer

(2014) Nathaniel M. Weathington et al.   JOURNAL OF CLINICAL INVESTIGATION

Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells

(2014) Yan Fang Sun et al.   PHYTOMEDICINE

A novel role of proteasomal β1 subunit in tumorigenesis

(2013) Fuqiang Yuan et al.   BIOSCIENCE REPORTS

Tetrandrine triggers apoptosis and cell cycle arrest in human renal cell carcinoma cells

(2013) Tao Chen et al.   Journal of Natural Medicines

Fangchinoline Induces G1 Arrest in Breast Cancer Cells Through Cell-Cycle Regulation

(2013) Zhibo Xing et al.   PHYTOTHERAPY RESEARCH

ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the signal network

(2013) L Feng et al.   Cell Death & Disease

The Potential of Tetrandrine Against Gliomas

(2012) Yun Chen et al.   Anti-Cancer Agents in Medicinal Chemistry

Therapeutic targeting of cancer cell cycle using proteasome inhibitors

(2012) Namrata Rastogi et al.   Cell Division

Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells

(2011) Ning Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fangchinoline Inhibits Breast Adenocarcinoma Proliferation by Inducing Apoptosis

(2011) Zhi-Bo Xing et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Fangchinoline Induced G1/S Arrest by Modulating Expression of p27, PCNA, and Cyclin D in Human Prostate Carcinoma Cancer PC3 Cells and Tumor Xenograft

(2010) Chang-Dong WANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Involvement of PI3K/AKT/GSK3ß pathway in tetrandrine-induced G1 arrest and apoptosis

(2010) Xuan Li Chen et al.   CANCER BIOLOGY & THERAPY

GSK-3β is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity

(2010) James A McCubrey et al.   CANCER BIOLOGY & THERAPY

Intrinsic apoptosis and NF-κB signaling are potential molecular targets for chemoprevention by black tea polyphenols in HepG2 cells in vitro and in a rat hepatocarcinogenesis model in vivo

(2010) R. Senthil Murugan et al.   FOOD AND CHEMICAL TOXICOLOGY

Tetrandrine Induces Apoptosis and Triggers Caspase Cascade in Human Bladder Cancer Cells

(2010) Xudong Li et al.   JOURNAL OF SURGICAL RESEARCH

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

(2010) Lynn Bedford et al.   NATURE REVIEWS DRUG DISCOVERY

Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice

(2009) Jiann-Ming Wu et al.   CANCER LETTERS

Anticancer effect of tetrandrine on primary cancer cells isolated from ascites and pleural fluids

(2008) Baorui Liu et al.   CANCER LETTERS

Interaction of Ganoderma triterpenes with doxorubicin and proteomic characterization of the possible molecular targets of Ganoderma triterpenes

(2008) Qing-Xi Yue et al.   CANCER SCIENCE