Inflammatory PAF Receptor Signaling Initiates Hedgehog Signaling and Kidney Fibrogenesis During Ethanol Consumption

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Myeloperoxidase formation of PAF receptor ligands induces PAF receptor-dependent kidney injury during ethanol consumption

(2015) Calivarathan Latchoumycandane et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans

(2015) Ming-Jiang Xu et al.   GASTROENTEROLOGY

Fibrosis in Nonalcoholic Fatty Liver Disease: Mechanisms and Clinical Implications

(2015) Paul Angulo et al.   SEMINARS IN LIVER DISEASE

Epidemiology ofDSM-5Alcohol Use Disorder

(2015) Bridget F. Grant et al.   JAMA Psychiatry

Animals Models of Gastrointestinal and Liver Diseases. Animal models of alcohol-induced liver disease: pathophysiology, translational relevance, and challenges

(2014) Stephanie Mathews et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation

(2014) Calivarathan Latchoumycandane et al.   FREE RADICAL BIOLOGY AND MEDICINE

Kidney Pericytes: Roles in Regeneration and Fibrosis

(2014) Rafael Kramann et al.   SEMINARS IN NEPHROLOGY

Potential Role of Hedgehog Pathway in Liver Response to Radiation

(2013) Sihyung Wang et al.   PLoS One

Hedgehog-Gli Pathway Activation during Kidney Fibrosis

(2012) Steven L. Fabian et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis

(2012) Angelika Horn et al.   ANNALS OF THE RHEUMATIC DISEASES

Bioactive oxidatively truncated phospholipids in inflammation and apoptosis: Formation, targets, and inactivation

(2012) Thomas M. McIntyre   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Crosstalk between TGF-β and hedgehog signaling in cancer

(2012) Delphine Javelaud et al.   FEBS LETTERS

Oxidatively Truncated Phospholipids Are Required Agents of Tumor Necrosis Factor α (TNFα)-induced Apoptosis

(2012) Calivarathan Latchoumycandane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sonic Hedgehog Signaling Mediates Epithelial-Mesenchymal Communication and Promotes Renal Fibrosis

(2012) H. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

(2012) Konstantin Stark et al.   NATURE IMMUNOLOGY

Biology of the renal pericyte

(2012) S. W. Smith et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Autocrine Sonic Hedgehog Attenuates Inflammation in Cerulein-Induced Acute Pancreatitis in Mice via Upregulation of IL-10

(2012) Xiangyu Zhou et al.   PLoS One

Acute Kidney Injury Is an Early Predictor of Mortality for Patients With Alcoholic Hepatitis

(2011) José Altamirano et al.   Clinical Gastroenterology and Hepatology

Mechanisms of fibrosis: the role of the pericyte

(2011) Claudia Schrimpf et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis

(2011) Yi-Ting Chen et al.   KIDNEY INTERNATIONAL

Up-Regulation of Sonic Hedgehog Contributes to TGF-β1-Induced Epithelial to Mesenchymal Transition in NSCLC Cells

(2011) Ma'in Y. Maitah et al.   PLoS One

Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice

(2010) Yongke Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of Hedgehog signaling in fibrogenic liver repair

(2010) Steve S. Choi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies

(2010) Vishal S Vaidya et al.   NATURE BIOTECHNOLOGY

Inhibition of Endogenous Hedgehog Signaling Protects Against Acute Liver Injury After Ischemia Reperfusion

(2010) Akshay Pratap et al.   PHARMACEUTICAL RESEARCH

Urothelial Cell Platelet-activating Factor Production Mediated by Calcium-independent Phospholipase A2γ

(2010) Prerna Rastogi et al.   UROLOGY

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

Alcoholic liver disease

(2009) Robert S. O'Shea et al.   HEPATOLOGY

Suppression of Mitochondrial Function by Oxidatively Truncated Phospholipids Is Reversible, Aided by Bid, and Suppressed by Bcl-XL

(2009) Rui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alcoholic Hepatitis

(2009) Michael R. Lucey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Platelet Activation by Low Concentrations of Intact Oxidized LDL Particles Involves the PAF Receptor

(2008) Rui Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

An early complement-dependent and TLR-4-independent phase in the pathogenesis of ethanol-induced liver injury in mice

(2008) Sanjoy Roychowdhury et al.   HEPATOLOGY

CYP2E1 and oxidative liver injury by alcohol

(2007) Yongke Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE