Concurrent Mutations in ATM and Genes Associated with Common γ Chain Signaling in Peripheral T Cell Lymphoma

Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells

(2015) Can Küçük et al.   Nature Communications

Rare occurrence of a STAT5B N642H mutation in adult T-cell acute lymphoblastic leukemia

(2015) Xiaolin Ma et al.   Cancer Genetics

PatternCNV: a versatile tool for detecting copy number changes from exome sequencing data

(2014) Chen Wang et al.   BIOINFORMATICS

Selective inhibitors of the Janus kinase Jak3—Are they effective?

(2014) Gebhard Thoma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia

(2014) M. J. Kiel et al.   BLOOD

PLCG1 mutations in cutaneous T-cell lymphomas

(2014) José P. Vaqué et al.   BLOOD

The RHOA G17V gene mutation occurs frequently in peripheral T-cell lymphoma and is associated with a characteristic molecular signature

(2014) R. Manso et al.   BLOOD

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model

(2014) S. Degryse et al.   BLOOD

FLAGS, frequently mutated genes in public exomes

(2014) Casper Shyr et al.   BMC Medical Genomics

Recurrent mutation ofJAK3in T-cell prolymphocytic leukemia

(2014) Anke K. Bergmann et al.   GENES CHROMOSOMES & CANCER

Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomas

(2014) R. Manso et al.   HAEMATOLOGICA

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse

(2014) O. R. Bandapalli et al.   HAEMATOLOGICA

From empiric to mechanism-based therapy for peripheral T cell lymphoma

(2014) Andrew M. Intlekofer et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

(2014) M Kontro et al.   LEUKEMIA

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

(2014) Teresa Palomero et al.   NATURE GENETICS

Detection of the G17V RHOA Mutation in Angioimmunoblastic T-Cell Lymphoma and Related Lymphomas Using Quantitative Allele-Specific PCR

(2014) Rie Nakamoto-Matsubara et al.   PLoS One

Molecular underpinning of extranodal NK/T-cell lymphoma

(2013) Yenlin Huang et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

A targeted mutational landscape of angioimmunoblastic T-cell lymphoma

(2013) O. Odejide et al.   BLOOD

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

(2013) H. L. M. Rajala et al.   BLOOD

ATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin

(2013) V. Navrkalova et al.   HAEMATOLOGICA

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

The JAK-STAT Transcriptional Regulator, STAT-5, Activates the ATM DNA Damage Pathway to Induce HPV 31 Genome Amplification upon Epithelial Differentiation

(2013) Shiyuan Hong et al.   PLoS Pathogens

Peripheral T-Cell Lymphomas: A Review of Current Approaches and Hopes for the Future

(2013) Alan P. Skarbnik et al.   Frontiers in Oncology

STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

(2012) A. Jerez et al.   BLOOD

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

(2012) G. Vasmatzis et al.   BLOOD

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Cytokines of the γc family control CD4+ T cell differentiation and function

(2012) Hidehiro Yamane et al.   NATURE IMMUNOLOGY

SomaticSTAT3Mutations in Large Granular Lymphocytic Leukemia

(2012) Hanna L.M. Koskela et al.   NEW ENGLAND JOURNAL OF MEDICINE

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Janus Kinase 3–Activating Mutations Identified in Natural Killer/T-cell Lymphoma

(2012) Ghee Chong Koo et al.   Cancer Discovery

CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer

(2011) Wing Chung Wong et al.   BIOINFORMATICS

Peripheral T-cell lymphoma

(2011) F. M. Foss et al.   BLOOD

Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin's lymphoma and T-cell non-Hodgkin's lymphoma

(2011) M. Kleppe et al.   HAEMATOLOGICA

Predicting the functional impact of protein mutations: application to cancer genomics

(2011) Boris Reva et al.   NUCLEIC ACIDS RESEARCH

Update: Peripheral T-Cell Lymphomas

(2011) Kerry J. Savage   Current Hematologic Malignancy Reports

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo

(2010) V. J. Weston et al.   BLOOD

Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM)

(2010) Hannah Carter et al.   CANCER BIOLOGY & THERAPY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Array-based genomic resequencing of human leukemia

(2010) Y Yamashita et al.   ONCOGENE

Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type

(2009) Y. Huang et al.   BLOOD