Large Neutral Amino Acid Supplementation Exerts Its Effect through Three Synergistic Mechanisms: Proof of Principle in Phenylketonuria Mice

Neurocognitive Evidence for Revision of Treatment Targets and Guidelines for Phenylketonuria

(2014) Rianne Jahja et al.   JOURNAL OF PEDIATRICS

Central and Systemic Responses to Methionine-Induced Hyperhomocysteinemia in Mice

(2014) Marina Mastelaro de Rezende et al.   PLoS One

Phenylketonuria: reduced tyrosine brain influx relates to reduced cerebral protein synthesis

(2013) Martijn J de Groot et al.   Orphanet Journal of Rare Diseases

Large Neutral Amino Acid Supplementation Increases Melatonin Synthesis in Phenylketonuria: A New Biomarker

(2012) Shoji Yano et al.   JOURNAL OF PEDIATRICS

Quantitative determination of free and total dopamine in human plasma by LC–MS/MS: the importance of sample preparation

(2011) Nico C van de Merbel et al.   Bioanalysis

Large neutral amino acids in the treatment of PKU: from theory to practice

(2010) Francjan J. van Spronsen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Phenylketonuria

(2010) Nenad Blau et al.   LANCET

5-Hydroxytryptophan rescues serotonin response to stress in prefrontal cortex of hyperphenylalaninaemic mice

(2009) Tiziana Pascucci et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Brain dysfunction in phenylketonuria: Is phenylalanine toxicity the only possible cause?

(2009) F. J. van Spronsen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Pathogenesis of cognitive dysfunction in phenylketonuria: Review of hypotheses☆

(2009) M.J. de Groot et al.   MOLECULAR GENETICS AND METABOLISM

Executive function in early-treated phenylketonuria: Profile and underlying mechanisms☆☆☆

(2009) Shawn E. Christ et al.   MOLECULAR GENETICS AND METABOLISM

Animal models of brain dysfunction in phenylketonuria☆

(2009) A.E. Martynyuk et al.   MOLECULAR GENETICS AND METABOLISM

The locus coeruleus and noradrenergic modulation of cognition

(2009) Susan J. Sara   NATURE REVIEWS NEUROSCIENCE