Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

BDNF impairment is associated with age-related changes in the inner retina and exacerbates experimental glaucoma

(2014) Vivek Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Rescue of Retinal Function by BDNF in a Mouse Model of Glaucoma

(2014) Luciano Domenici et al.   PLoS One

Neuronal Signaling through Endocytosis

(2014) K. E. Cosker et al.   Cold Spring Harbor Perspectives in Biology

Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

(2013) Dominik F. Aschauer et al.   PLoS One

Neurotrophin Signaling via Long-Distance Axonal Transport

(2012) Praveen D. Chowdary et al.   Annual Review of Physical Chemistry

Truncated TrkB: Beyond a dominant negative receptor

(2012) Barbara M. Fenner   CYTOKINE & GROWTH FACTOR REVIEWS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target

(2012) S.D. Crish et al.   NEUROSCIENCE

Axotomy-induced retinal ganglion cell death in adult mice: Quantitative and topographic time course analyses

(2011) C. Galindo-Romero et al.   EXPERIMENTAL EYE RESEARCH

Novel adeno-associated viral vectors for retinal gene therapy

(2011) L H Vandenberghe et al.   GENE THERAPY

Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9

(2011) A Van der Perren et al.   GENE THERAPY

Glaucoma

(2011) Harry A Quigley   LANCET

The molecular basis of retinal ganglion cell death in glaucoma

(2011) Mohammadali Almasieh et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Understanding glaucomatous damage: Anatomical and functional data from ocular hypertensive rodent retinas

(2011) Manuel Vidal-Sanz et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration

(2011) Chikako Harada et al.   Nature Communications

Changes in the inner and outer retinal layers after acute increase of the intraocular pressure in adult albino Swiss mice

(2010) Nicolás Cuenca et al.   EXPERIMENTAL EYE RESEARCH

Neurotrophic factor delivery as a protective treatment for glaucoma

(2010) Thomas V. Johnson et al.   EXPERIMENTAL EYE RESEARCH

Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction

(2010) Niclas Lindqvist et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Rodent models of glaucoma

(2009) Thomas V. Johnson et al.   BRAIN RESEARCH BULLETIN

Topography of neuron loss in the retinal ganglion cell layer in human glaucoma

(2009) Y Lei et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Neurotrophin roles in retinal ganglion cell survival: Lessons from rat glaucoma models

(2009) Elaine C. Johnson et al.   EXPERIMENTAL EYE RESEARCH

Does elevated intraocular pressure reduce retinal TRKB-mediated survival signaling in experimental glaucoma?

(2009) Ying Guo et al.   EXPERIMENTAL EYE RESEARCH

Effects of different neurotrophic factors on the survival of retinal ganglion cells after a complete intraorbital nerve crush injury: A quantitative in vivo study

(2009) Guillermo Parrilla-Reverter et al.   EXPERIMENTAL EYE RESEARCH

Time-course of the retinal nerve fibre layer degeneration after complete intra-orbital optic nerve transection or crush: A comparative study

(2009) Guillermo Parrilla-Reverter et al.   VISION RESEARCH

Retinal ganglion cell population in adult albino and pigmented mice: A computerized analysis of the entire population and its spatial distribution

(2009) M. Salinas-Navarro et al.   VISION RESEARCH

Degenerative alterations in the visual pathway after NMDA-induced retinal damage in mice

(2008) Yasushi Ito et al.   BRAIN RESEARCH

A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats

(2008) M. Salinas-Navarro et al.   VISION RESEARCH