Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression
Authors
Keywords
Cancer treatment, DNA methylation, Gene expression, Cancer stem cells, Cell cycle and cell division, G1 phase, Methylation, Glioblastoma multiforme
Journal
PLoS One
Volume 10, Issue 10, Pages e0140131
Publisher
Public Library of Science (PLoS)
Online
2015-10-09
DOI
10.1371/journal.pone.0140131
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma
- (2015) Yoshinari Shinsato et al. Oncotarget
- Key determinants of short-term and long-term glioblastoma survival: A 14-year retrospective study of patients from the Hermelin Brain Tumor Center at Henry Ford Hospital
- (2014) Paul Mazaris et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- MGMT testing—the challenges for biomarker-based glioma treatment
- (2014) Wolfgang Wick et al. Nature Reviews Neurology
- The Predictive but Not Prognostic Value of MGMT Promoter Methylation Status in Elderly Glioblastoma Patients: A Meta-Analysis
- (2014) An-an Yin et al. PLoS One
- RETRACTED ARTICLE: Prognostic value of CD133 expression in cancer patients treated with chemoradiotherapy: a meta-analysis
- (2014) Jin-Hai Zhai et al. TUMOR BIOLOGY
- Research on DNA methylation of human osteosarcoma cell MGMT and its relationship with cell resistance to alkylating agents
- (2013) Jun Guo et al. Biochemistry and Cell Biology
- Temozolomide down-regulates P-glycoprotein in human blood–brain barrier cells by disrupting Wnt3 signaling
- (2013) Chiara Riganti et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives
- (2013) Ziyad Binkhathlan et al. CURRENT CANCER DRUG TARGETS
- Altered Expression of MGMT in High-Grade Gliomas Results from the Combined Effect of Epigenetic and Genetic Aberrations
- (2013) João Ramalho-Carvalho et al. PLoS One
- Gene analysis and dynamics of tumor stem cells in human glioblastoma cells after radiation
- (2013) Akiko Sasaki et al. Human Cell
- Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours
- (2012) A O von Bueren et al. BRITISH JOURNAL OF CANCER
- Impact of Temozolomide on Immune Response during Malignant Glioma Chemotherapy
- (2012) Sadhak Sengupta et al. Clinical & Developmental Immunology
- Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells
- (2012) Caroline Happold et al. JOURNAL OF NEUROCHEMISTRY
- MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy
- (2012) Consolación Melguizo et al. Journal of Translational Medicine
- CD133 as a Marker for Regulation and Potential for Targeted Therapies in Glioblastoma Multiforme
- (2012) Winward Choy et al. NEUROSURGERY CLINICS OF NORTH AMERICA
- Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma
- (2012) Koji Yoshimoto et al. Frontiers in Oncology
- Mechanism of Cell Adaptation
- (2011) Valentina Fodale et al. CANCER JOURNAL
- Noscapine inhibits tumor growth in TMZ-resistant gliomas
- (2011) Niyati Jhaveri et al. CANCER LETTERS
- Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision Repair
- (2011) E. M. Goellner et al. CANCER RESEARCH
- Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma
- (2011) Miyuki Uno et al. Clinics
- Glioblastoma survival in the United States before and during the temozolomide era
- (2011) Derek R. Johnson et al. JOURNAL OF NEURO-ONCOLOGY
- O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients
- (2011) S. Spiegl-Kreinecker et al. NEURO-ONCOLOGY
- The presence of stem cell marker-expressing cells is not prognostically significant in glioblastomas
- (2011) Kyung-Jung Kim et al. NEUROPATHOLOGY
- Temozolomide: Mechanisms of Action, Repair and Resistance
- (2011) Jihong Zhang et al. Current Molecular Pharmacology
- MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase-Mediated HOX/Stem Cell Gene Signature
- (2010) N. Gaspar et al. CANCER RESEARCH
- Gene expression profiling predicts response to temozolomide in malignant gliomas
- (2010) Yoshino INTERNATIONAL JOURNAL OF ONCOLOGY
- Activation of AMP-activated Protein Kinase by Temozolomide Contributes to Apoptosis in Glioblastoma Cells via p53 Activation and mTORC1 Inhibition
- (2010) Wen-bin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MSH6 Mutations Arise in Glioblastomas during Temozolomide Therapy and Mediate Temozolomide Resistance
- (2009) S. Yip et al. CLINICAL CANCER RESEARCH
- Calcium dysregulation induces apoptosis-inducing factor release: Cross-talk between PARP-1- and calpain- signaling pathways
- (2009) Peter S. Vosler et al. EXPERIMENTAL NEUROLOGY
- DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome
- (2009) George Poulogiannis et al. HISTOPATHOLOGY
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Temozolomide with Radiation Therapy in High Grade Brain Gliomas: Pharmaceuticals Considerations and Efficacy;A Review Article
- (2009) Georgios Koukourakis et al. MOLECULES
- Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents
- (2009) Sharada D. Vangipuram et al. PEDIATRIC BLOOD & CANCER
- Mismatch Repair Deficiency Does Not Mediate Clinical Resistance to Temozolomide in Malignant Glioma
- (2008) J. A. Maxwell et al. CLINICAL CANCER RESEARCH
- Glioblastoma in adults
- (2008) Alba A. Brandes et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Verapamil Inhibits L-type Calcium Channel Mediated Apoptosis in Human Colon Cancer Cells
- (2008) Antoni Zawadzki et al. DISEASES OF THE COLON & RECTUM
- Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity
- (2008) Monika E. Hegi et al. JOURNAL OF CLINICAL ONCOLOGY
- Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma
- (2008) Anastasia Murat et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas
- (2008) Kyeung Min Joo et al. LABORATORY INVESTIGATION
- DNA mismatch repair: Molecular mechanism, cancer, and ageing
- (2008) Peggy Hsieh et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Prognostic significance of the immunohistochemical expression ofO6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas
- (2008) Takao Nakagawa et al. NEUROPATHOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now