Structure and Function of p53-DNA Complexes with Inactivation and Rescue Mutations: A Molecular Dynamics Simulation Study

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors

(2015) Valeria G. Antico Arciuch et al.   Oncotarget

Mantle cell lymphoma-like lymphomas in c-myc-3’RR/p53+/- mice and c-myc-3’RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin

(2015) Pauline Rouaud et al.   Oncotarget

Absence of a simple code: how transcription factors read the genome

(2014) Matthew Slattery et al.   TRENDS IN BIOCHEMICAL SCIENCES

Non-Cell-Autonomous Tumor Suppression by p53

(2013) Amaia Lujambio et al.   CELL

Investigation of Binding Phenomenon of NSP3 and p130Cas Mutants and Their Effect on Cell Signalling

(2013) Balu K. et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

In-silico screening of cancer associated mutation on PLK1 protein and its structural consequences

(2013) Balu Kamaraj et al.   JOURNAL OF MOLECULAR MODELING

Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions

(2013) A. Eldar et al.   NUCLEIC ACIDS RESEARCH

Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes

(2012) Ana Carolina Dantas Machado et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Tumor Suppression by p53: Fall of the Triumvirate?

(2012) Andreas K. Hock et al.   CELL

p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP

(2012) Harsha S. Madapura et al.   CELL CYCLE

Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours

(2012) Paul Krimpenfort et al.   NATURE

TP53 PIN3 and PEX4 polymorphisms and infertility associated with endometriosis or with post-in vitro fertilization implantation failure

(2012) D D Paskulin et al.   Cell Death & Disease

In silico investigation of molecular mechanism of laminopathy caused by a point mutation (R482W) in lamin A/C protein

(2011) Vidya Rajendran et al.   AMINO ACIDS

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity

(2011) Tom J Petty et al.   EMBO JOURNAL

CKIα ablation highlights a critical role for p53 in invasiveness control

(2011) Ela Elyada et al.   NATURE

Cancer: The blind spot of p53

(2010) Anton Berns   NATURE

Selective activation of p53-mediated tumour suppression in high-grade tumours

(2010) Melissa R. Junttila et al.   NATURE

Stage-specific sensitivity to p53 restoration during lung cancer progression

(2010) David M. Feldser et al.   NATURE

The HADDOCK web server for data-driven biomolecular docking

(2010) Sjoerd J de Vries et al.   Nature Protocols

Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs

(2010) Malka Kitayner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal Structure of the p53 Core Domain Bound to a Full Consensus Site as a Self-Assembled Tetramer

(2010) Yongheng Chen et al.   STRUCTURE

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

p53: A Guide to Apoptosis

(2008) Erik Meulmeester et al.   CURRENT CANCER DRUG TARGETS

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Crystal structure of a p53 core tetramer bound to DNA

(2008) K A Malecka et al.   ONCOGENE