Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

Chromogens in Multiple Immunohistochemical Staining Used for Visual Assessment and Spectral Imaging: The Colorful Future

(2014) Chris M. van der Loos   JOURNAL OF HISTOTECHNOLOGY

Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease

(2014) Pramod K. Mistry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role ofSCARB2as susceptibility factor in Parkinson's disease

(2013) Franziska Hopfner et al.   MOVEMENT DISORDERS

Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease

(2013) Yildiz Yildiz et al.   Orphanet Journal of Rare Diseases

Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease

(2013) Sovan Sarkar et al.   Cell Reports

A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies

(2013) Michael A. Nalls et al.   JAMA Neurology

Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining β-Exoglucosidases In Situ and In Vivo

(2012) Wouter W. Kallemeijn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments inFmr1KO mice

(2012) M. F. Vinueza Veloz et al.   GENES BRAIN AND BEHAVIOR

The Non-lysosomal β-Glucosidase GBA2 Is a Non-integral Membrane-associated Protein at the Endoplasmic Reticulum (ER) and Golgi

(2012) Heinz G. Körschen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes

(2012) Derek G. Burke et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Iminosugar-based inhibitors of glucosylceramide synthase prolong survival but paradoxically increase brain glucosylceramide levels in Niemann–Pick C mice

(2012) Jennifer B. Nietupski et al.   MOLECULAR GENETICS AND METABOLISM

Npc1 deficiency in the C57BL/6J genetic background enhances Niemann–Pick disease type C spleen pathology

(2011) Julio Parra et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

(2011) N. Dekker et al.   BLOOD

Spatiotemporal firing patterns in the cerebellum

(2011) Chris I. De Zeeuw et al.   NATURE REVIEWS NEUROSCIENCE

Iminosugar-Based Inhibitors of Glucosylceramide Synthase Increase Brain Glycosphingolipids and Survival in a Mouse Model of Sandhoff Disease

(2011) Karen M. Ashe et al.   PLoS One

Ultrasensitive in situ visualization of active glucocerebrosidase molecules

(2010) Martin D Witte et al.   Nature Chemical Biology

Niemann-Pick disease type C

(2010) Marie T Vanier   Orphanet Journal of Rare Diseases

Cerebellar cortical organization: a one-map hypothesis

(2009) Richard Apps et al.   NATURE REVIEWS NEUROSCIENCE

Prominent increase in plasma ganglioside GM3 is associated with clinical manifestations of type I Gaucher disease

(2008) Karen Ghauharali-van der Vlugt et al.   CLINICA CHIMICA ACTA

Role of Olivary Electrical Coupling in Cerebellar Motor Learning

(2008) Ruben S. Van Der Giessen et al.   NEURON