The Chromone Alkaloid, Rohitukine, Affords Anti-Cancer Activity via Modulating Apoptosis Pathways in A549 Cell Line and Yeast Mitogen Activated Protein Kinase (MAPK) Pathway

Systematic humanization of yeast genes reveals conserved functions and genetic modularity

(2015) A. H. Kachroo et al.   SCIENCE

Environmental Toxicants as Extrinsic Epigenetic Factors for Parkinsonism: Studies Employing Transgenic C. elegans Model

(2013) Pooja Jadiya et al.   CNS & Neurological Disorders-Drug Targets

Saccharomyces cerevisiae as a model system to study the response to anticancer agents

(2012) Renata Matuo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells

(2012) Li Yuan et al.   FOOD AND CHEMICAL TOXICOLOGY

Mitochondrial release of the NADH dehydrogenase Ndi1 induces apoptosis in yeast

(2012) Yixian Cui et al.   MOLECULAR BIOLOGY OF THE CELL

Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity

(2011) Patel Mohana Kumara et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

The Evolving War on Cancer

(2011) Daniel A. Haber et al.   CELL

Saccharomyces cerevisiae as a Model Organism: A Comparative Study

(2011) Hiren Karathia et al.   PLoS One

Rewiring of Genetic Networks in Response to DNA Damage

(2010) S. Bandyopadhyay et al.   SCIENCE

Dysoxylum binectariferum Hook.f (Meliaceae), a rich source of rohitukine

(2009) Patel Mohanakumara et al.   FITOTERAPIA

The High Osmotic Response and Cell Wall Integrity Pathways Cooperate to Regulate Transcriptional Responses to Zymolyase-induced Cell Wall Stress inSaccharomyces cerevisiae

(2009) Raúl García et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitogen-activated Protein Kinase Inhibitors Induce Apoptosis and Enhance the Diallyl Disulfide-induced Apoptotic Effect in Human CNE2 Cells

(2008) Jun Wen et al.   JOURNAL OF HEALTH SCIENCE

Enhancing Drug Accumulation in Saccharomyces cerevisiae by Repression of Pleiotropic Drug Resistance Genes with Chimeric Transcription Repressors

(2008) A. Stepanov et al.   MOLECULAR PHARMACOLOGY

Flavopiridol Suppresses Tumor Necrosis Factor-Induced Activation of Activator Protein-1, c-Jun N-Terminal Kinase, p38 Mitogen-Activated Protein Kinase (MAPK), p44/p42 MAPK, and Akt, Inhibits Expression of Antiapoptotic Gene Products, and Enhances Apoptosis through Cytochrome c Release and Caspase Activation in Human Myeloid Cells

(2008) Y. Takada et al.   MOLECULAR PHARMACOLOGY