Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling

Combinatorial antitumor effect of HDAC and the PI3K-Akt-mTOR pathway inhibition in a Pten defecient model of prostate cancer

(2015) Leigh Ellis et al.   Oncotarget

Aspects on gallbladder cancer in 2014

(2014) Åke Andrén-Sandberg et al.   CURRENT OPINION IN GASTROENTEROLOGY

mTOR inhibitors in cancer therapy

(2012) Yekaterina Y. Zaytseva et al.   CANCER LETTERS

The therapeutic effect of histone deacetylase inhibitor PCI-24781 on gallbladder carcinoma in BK5.erbB2 mice

(2012) Takuya Kitamura et al.   JOURNAL OF HEPATOLOGY

P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells

(2012) K. Bajbouj et al.   JOURNAL OF NEURO-ONCOLOGY

Preclinical evaluation of dual PI3K-mTOR inhibitors and histone deacetylase inhibitors in head and neck squamous cell carcinoma

(2011) R B Erlich et al.   BRITISH JOURNAL OF CANCER

Vascular endothelial growth factor-D promotes growth, lymphangiogenesis and lymphatic metastasis in gallbladder cancer

(2011) Wei Lin et al.   CANCER LETTERS

NBM-HD-3, a novel histone deacetylase inhibitor with anticancer activity through modulation of PTEN and AKT in brain cancer cells

(2011) Wei-Jan Huang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Macrocyclic Histone Deacetylase Inhibitors

(2010) Sandra C. Mwakwari et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Gallbladder Cancer: Differences in Presentation, Surgical Treatment, and Survival in Patients Treated at Centers in Three Countries

(2010) Jean M. Butte et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2

(2009) M. Gupta et al.   BLOOD

Histone deacetylase inhibitors as anti-neoplastic agents

(2009) Nicolas Batty et al.   CANCER LETTERS

Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma

(2009) Junpei Yamaguchi et al.   CANCER SCIENCE

The PKB/AKT Pathway in Cancer

(2009) Amancio Carnero   CURRENT PHARMACEUTICAL DESIGN

HDAC family: What are the cancer relevant targets?

(2008) Olaf Witt et al.   CANCER LETTERS

Histone deacetylase inhibitors: possible implications for neurodegenerative disorders

(2008) Eric Hahnen et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Surgery for Gallbladder Cancer: A Population-Based Analysis

(2008) Natalie G. Coburn et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells

(2008) C Nishioka et al.   LEUKEMIA