LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice

A Short Splice Form of Xin-Actin Binding Repeat Containing 2 (XIRP2) Lacking the Xin Repeats Is Required for Maintenance of Stereocilia Morphology and Hearing Function

(2015) S. P. Francis et al.   JOURNAL OF NEUROSCIENCE

Inner ear hair cells deteriorate in mice engineered to have no or diminished innervation

(2015) Jennifer Kersigo et al.   Frontiers in Aging Neuroscience

Maintenance of stereocilia and apical junctional complexes by Cdc42 in cochlear hair cells

(2014) T. Ueyama et al.   JOURNAL OF CELL SCIENCE

Staurosporine-induced collapse of cochlear hair bundles

(2014) Richard J. Goodyear et al.   JOURNAL OF COMPARATIVE NEUROLOGY

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice

(2014) Chen Sun et al.   NEUROREPORT

New strategies for the restoration of hearing loss: challenges and opportunities

(2013) M. N. Rivolta   BRITISH MEDICAL BULLETIN

 -Actin and Fascin-2 Cooperate to Maintain Stereocilia Length

(2013) B. J. Perrin et al.   JOURNAL OF NEUROSCIENCE

Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2

(2013) David N. Furness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism

(2013) Zhubing Shi et al.   STRUCTURE

Adaptor Protein Cerebral Cavernous Malformation 3 (CCM3) Mediates Phosphorylation of the Cytoskeletal Proteins Ezrin/Radixin/Moesin by Mammalian Ste20-4 to Protect Cells from Oxidative Stress

(2012) Miguel Fidalgo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rap2A links intestinal cell polarity to brush border formation

(2012) Martijn Gloerich et al.   NATURE CELL BIOLOGY

Age-Related Primary Cochlear Neuronal Degeneration in Human Temporal Bones

(2011) Chadi A. Makary et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Polycystin-1 Is Required for Stereocilia Structure But Not for Mechanotransduction in Inner Ear Hair Cells

(2011) K. A. Steigelman et al.   JOURNAL OF NEUROSCIENCE

Roles of the Espin Actin-Bundling Proteins in the Morphogenesis and Stabilization of Hair Cell Stereocilia Revealed in CBA/CaJ Congenic Jerker Mice

(2011) Gabriella Sekerková et al.   PLoS Genetics

Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

(2010) Shin-ichiro Kitajiri et al.   CELL

RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis

(2010) G. Sun et al.   Disease Models & Mechanisms

Generation and characterization of Atoh1-Cre knock-in mouse line

(2010) Hua Yang et al.   GENESIS

LKB1 Deficiency in Tie2-Cre-expressing Cells Impairs Ischemia-induced Angiogenesis

(2010) Koji Ohashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization Complex

(2009) Jean Paul ten Klooster et al.   DEVELOPMENTAL CELL

Cardiac-specific Deletion of LKB1 Leads to Hypertrophy and Dysfunction

(2009) Yasumasa Ikeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Twinfilin 2 Regulates Actin Filament Lengths in Cochlear Stereocilia

(2009) A. W. Peng et al.   JOURNAL OF NEUROSCIENCE

Linking genes underlying deafness to hair-bundle development and function

(2009) Christine Petit et al.   NATURE NEUROSCIENCE

Somatic LKB1 Mutations Promote Cervical Cancer Progression

(2009) Shana N. Wingo et al.   PLoS One

Ezrin/radixin/moesin: Versatile controllers of signaling molecules and of the cortical cytoskeleton

(2007) Verena Niggli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY