Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells

CD44 Deficiency Contributes to Enhanced Experimental Autoimmune Encephalomyelitis

(2013) Kelly M. Flynn et al.   AMERICAN JOURNAL OF PATHOLOGY

CD4+T-cell subsets in transplantation

(2013) Zhongmin Liu et al.   IMMUNOLOGICAL REVIEWS

Regulation of Antigen-Experienced T Cells: Lessons from the Quintessential Memory Marker CD44

(2012) Bas J. G. Baaten et al.   Frontiers in Immunology

T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4ig but is successfully treated by interleukin-17 neutralization

(2011) Marije I. Koenders et al.   ARTHRITIS AND RHEUMATISM

CD44 is critical for airway accumulation of antigen-specific Th2, but not Th1, cells induced by antigen challenge in mice

(2011) Shigeki Katoh et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD44 Reciprocally Regulates the Differentiation of Encephalitogenic Th1/Th17 and Th2/Regulatory T Cells through Epigenetic Modulation Involving DNA Methylation of Cytokine Gene Promoters, Thereby Controlling the Development of Experimental Autoimmune Encephalomyelitis

(2011) H. Guan et al.   JOURNAL OF IMMUNOLOGY

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Low-strength T-cell activation promotes Th17 responses

(2010) H. A. Purvis et al.   BLOOD

CD44 Regulates Survival and Memory Development in Th1 Cells

(2010) Bas J.G. Baaten et al.   IMMUNITY

CD44 interacts directly with Lck in a zinc-dependent manner

(2010) Dennis C. Lefebvre et al.   MOLECULAR IMMUNOLOGY

T-cell phenotype in protocol renal biopsy from transplant recipients treated with belatacept-mediated co-stimulatory blockade

(2010) P. Grimbert et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Regulation of Zap70 Expression During Thymocyte Development Enables Temporal Separation of CD4 and CD8 Repertoire Selection at Different Signaling Thresholds

(2010) M. Saini et al.   Science Signaling

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Heterogeneity and plasticity of T helper cells

(2009) Jinfang Zhu et al.   CELL RESEARCH

Differential Expression of Interleukin-17A and -17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase

(2009) Julio Gomez-Rodriguez et al.   IMMUNITY

ICOS Deficiency Results in Exacerbated IL-17 Mediated Experimental Autoimmune Encephalomyelitis

(2009) Georgina Galicia et al.   JOURNAL OF CLINICAL IMMUNOLOGY

A Major Lipid Raft Protein Raftlin Modulates T Cell Receptor Signaling and Enhances Th17-Mediated Autoimmune Responses

(2009) Kazuko Saeki et al.   JOURNAL OF IMMUNOLOGY

Role of CD44 in the Differentiation of Th1 and Th2 Cells: CD44-Deficiency Enhances the Development of Th2 Effectors in Response to Sheep RBC and Chicken Ovalbumin

(2009) H. Guan et al.   JOURNAL OF IMMUNOLOGY

CD28 Co-Stimulation Down Regulates Th17 Development

(2009) Salim Bouguermouh et al.   PLoS One

CD40–CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

(2009) Giandomenica Iezzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pathogenic role of IL- 17 at the early stage of corneal allograft rejection

(2009) Haiyong Chen et al.   TRANSPLANT IMMUNOLOGY

CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation

(2008) Venkatesh L. Hegde et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY