AdHu5Ag85A Respiratory Mucosal Boost Immunization Enhances Protection against Pulmonary Tuberculosis in BCG-Primed Non-Human Primates

New Approaches to TB Vaccination

(2014) Zhou Xing et al.   CHEST

Aerosol Vaccination with AERAS-402 Elicits Robust Cellular Immune Responses in the Lungs of Rhesus Macaques but Fails To Protect against High-DoseMycobacterium tuberculosisChallenge

(2014) Patricia A. Darrah et al.   JOURNAL OF IMMUNOLOGY

Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial

(2014) Iman Satti et al.   LANCET INFECTIOUS DISEASES

Mycobacterium tuberculosis Erdman infection of rhesus macaques of Chinese origin

(2014) Jing Zhang et al.   TUBERCULOSIS

Modeling Tuberculosis in Nonhuman Primates

(2014) C. A. Scanga et al.   Cold Spring Harbor Perspectives in Medicine

Evaluation of the Safety and Immunogenicity of a Candidate Tuberculosis Vaccine, MVA85A, Delivered by Aerosol to the Lungs of Macaques

(2013) A. D. White et al.   Clinical and Vaccine Immunology

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Harnessing local and systemic immunity for vaccines against tuberculosis

(2013) P C L Beverley et al.   Mucosal Immunology

A Human Type 5 Adenovirus-Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity

(2013) F. Smaill et al.   Science Translational Medicine

Tuberculosis vaccines: Time to think about the next generation

(2013) Stefan H.E. Kaufmann   SEMINARS IN IMMUNOLOGY

Comparison of the immunogenicity and protection against bovine tuberculosis following immunization by BCG-priming and boosting with adenovirus or protein based vaccines

(2013) G. Dean et al.   VACCINE

Understanding Delayed T-Cell Priming, Lung Recruitment, and Airway Luminal T-Cell Responses in Host Defense against Pulmonary Tuberculosis

(2012) Christopher R. Shaler et al.   Clinical & Developmental Immunology

Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity

(2012) M. J. Johnson et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of delayed anti-tuberculosis protection in the lung of parenteral BCG-vaccinated hosts: A critical role of airway luminal T cells

(2012) C N Horvath et al.   Mucosal Immunology

Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity

(2012) M Jeyanathan et al.   Mucosal Immunology

Tuberculosis Vaccines: A Strategic Blueprint for the Next Decade

(2012) Michael J. Brennan et al.   TUBERCULOSIS

Stereological analysis of bacterial load and lung lesions in nonhuman primates (rhesus macaques) experimentally infected with Mycobacterium tuberculosis

(2011) Paul A. Luciw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Initiation and regulation of T-cell responses in tuberculosis

(2011) K B Urdahl et al.   Mucosal Immunology

The Novel Tuberculosis Vaccine, AERAS-402, Induces Robust and Polyfunctional CD4+and CD8+T Cells in Adults

(2010) Brian Abel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

(2010) Lis R.V. Antonelli et al.   JOURNAL OF CLINICAL INVESTIGATION

Airway luminal T cells: A newcomer on the stage of TB vaccination strategies

(2010) Mangalakumari Jeyanathan et al.   TRENDS IN IMMUNOLOGY

MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

(2009) Frank A. W. Verreck et al.   PLoS One

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

(2009) S. G. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

rBCG Induces Strong Antigen-Specific T Cell Responses in Rhesus Macaques in a Prime-Boost Setting with an Adenovirus 35 Tuberculosis Vaccine Vector

(2008) Isabelle Magalhaes et al.   PLoS One

Immunogenicity and safety of aerosolized measles vaccine: Systematic review and meta-analysis

(2007) Nicola Low et al.   VACCINE