mLST8 Promotes mTOR-Mediated Tumor Progression

SIN1 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition

(2013) Jiangfeng Xu et al.   CANCER

A role for Raptor phosphorylation in the mechanical activation of mTOR signaling

(2013) John W. Frey et al.   CELLULAR SIGNALLING

Genetic variations of mTORC1 genes and risk of gastric cancer in an eastern chinese population

(2013) Jing He et al.   MOLECULAR CARCINOGENESIS

mTOR kinase structure, mechanism and regulation

(2013) Haijuan Yang et al.   NATURE

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

(2013) Pengda Liu et al.   NATURE CELL BIOLOGY

MiR-424/503-Mediated Rictor Upregulation Promotes Tumor Progression

(2013) Chitose Oneyama et al.   PLoS One

Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis

(2013) A. M. Robitaille et al.   SCIENCE

The Tumor Suppressive MicroRNA miR-218 Targets the mTOR Component Rictor and Inhibits AKT Phosphorylation in Oral Cancer

(2011) A. Uesugi et al.   CANCER RESEARCH

miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer

(2011) T. Tsuruta et al.   CANCER RESEARCH

mTOR-RAPTOR and 14-3-3  immunohistochemical expression in high grade prostatic intraepithelial neoplasia and prostatic adenocarcinomas: a tissue microarray study

(2011) S. Evren et al.   JOURNAL OF CLINICAL PATHOLOGY

MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression

(2011) C Oneyama et al.   ONCOGENE

MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways

(2011) C Oneyama et al.   ONCOGENE

S6K1 and 4E-BP1 Are Independent Regulated and Control Cellular Growth in Bladder Cancer

(2011) Roman Nawroth et al.   PLoS One

Energy Balance, the PI3K-AKT-mTOR Pathway Genes, and the Risk of Bladder Cancer

(2010) J. Lin et al.   Cancer Prevention Research

MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2010) Francesca Fornari et al.   CANCER RESEARCH

Regulation of Insulin-like Growth Factor–Mammalian Target of Rapamycin Signaling by MicroRNA in Childhood Adrenocortical Tumors

(2010) Mabrouka Doghman et al.   CANCER RESEARCH

Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR , PTEN , STK11 , RPKAA1 , PRKAG2 , TSC1 , TSC2 , PI3K and Akt1

(2010) Martha L. Slattery et al.   CARCINOGENESIS

A Link between mir-100 and FRAP1/mTOR in Clear Cell Ovarian Cancer

(2010) Ankur K. Nagaraja et al.   MOLECULAR ENDOCRINOLOGY

mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice

(2009) David A. Guertin et al.   CANCER CELL

Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk

(2009) Meng Chen et al.   CARCINOGENESIS

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

The Pharmacology of mTOR Inhibition

(2009) D. A. Guertin et al.   Science Signaling

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

(2008) Valeria Facchinetti et al.   EMBO JOURNAL