Cardiac Fibrosis Alleviated by Exercise Training Is AMPK-Dependent

Expression of lipogenic genes is upregulated in the heart with exercise training-induced but not pressure overload-induced left ventricular hypertrophy

(2013) Pawel Dobrzyn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial biogenesis and PGC-1α deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle

(2011) Ling Li et al.   BASIC RESEARCH IN CARDIOLOGY

Metformin inhibits P-glycoprotein expression via the NF-κB pathway and CRE transcriptional activity through AMPK activation

(2010) Hyung Gyun Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Myocardial oxidative stress contributes to transgenic β2-adrenoceptor activation-induced cardiomyopathy and heart failure

(2010) Q Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway

(2010) Han Xiao et al.   CARDIOVASCULAR RESEARCH

AMPKα2 Deletion Causes Aberrant Expression and Activation of NAD(P)H Oxidase and Consequent Endothelial Dysfunction In Vivo

(2010) Shuangxi Wang et al.   CIRCULATION RESEARCH

Upregulation of Nox4 by Hypertrophic Stimuli Promotes Apoptosis and Mitochondrial Dysfunction in Cardiac Myocytes

(2010) Tetsuro Ago et al.   CIRCULATION RESEARCH

Exercise training reduces fibrosis and matrix metalloproteinase dysregulation in the aging rat heart

(2010) Hyo-Bum Kwak et al.   FASEB JOURNAL

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin Prevents Progression of Heart Failure in Dogs

(2009) Hideyuki Sasaki et al.   CIRCULATION

Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid-Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin

(2009) X.-N. Li et al.   DIABETES

Peroxisome proliferator-activated receptors γ and α agonists stimulate cardiac glucose uptake via activation of AMP-activated protein kinase☆

(2009) Xiaoyan Xiao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Adiponectin Decreases C-Reactive Protein Synthesis and Secretion From Endothelial Cells

(2008) Sridevi Devaraj et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Late exercise training improves non-uniformity of transmural myocardial function in rats with ischaemic heart failure

(2008) Younss Aït Mou et al.   CARDIOVASCULAR RESEARCH

Exercise training combined with angiotensin II receptor blockade limits post-infarct ventricular remodelling in rats

(2008) X. Xu et al.   CARDIOVASCULAR RESEARCH

Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure

(2008) Susheel Gundewar et al.   CIRCULATION RESEARCH

AMP Activated Protein Kinase-α2 Deficiency Exacerbates Pressure-Overload–Induced Left Ventricular Hypertrophy and Dysfunction in Mice

(2008) Ping Zhang et al.   HYPERTENSION

Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor κB activation

(2008) Susan V. Brooks et al.   JOURNAL OF PHYSIOLOGY-LONDON

Systemic adaptation to oxidative challenge induced by regular exercise

(2007) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training

(2007) Mari-Carmen Gomez-Cabrera et al.   FREE RADICAL BIOLOGY AND MEDICINE