Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform

Microfluidic chip-based technologies: emerging platforms for cancer diagnosis

(2013) Li Ying et al.   BMC BIOTECHNOLOGY

Functional Investigation of NCI-H460-Inducible Myofibroblasts on the Chemoresistance to VP-16 with a Microfluidic 3D Co-Culture Device

(2013) Yuanyuan Hao et al.   PLoS One

GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling

(2012) Kyle T. Pfaffenbach et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Rationale Behind Targeting Fibroblast Activation Protein-Expressing Carcinoma-Associated Fibroblasts as a Novel Chemotherapeutic Strategy

(2012) W. N. Brennen et al.   MOLECULAR CANCER THERAPEUTICS

miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer

(2012) S-F Su et al.   ONCOGENE

Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling

(2011) S. Wey et al.   BLOOD

Abnormality of the hepatocyte growth factor/MET pathway in pulmonary adenocarcinogenesis

(2011) Keisei Tachibana et al.   LUNG CANCER

Stromal Endothelial Cells Directly Influence Cancer Progression

(2011) J. W. Franses et al.   Science Translational Medicine

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Modulation of cell sensitivity to antitumor agents by targeting survival pathways

(2010) Paola Perego et al.   BIOCHEMICAL PHARMACOLOGY

Chemotherapy resistance research of lung cancer based on micro-fluidic chip system with flow medium

(2010) Long Zhao et al.   BIOMEDICAL MICRODEVICES

Fibroblasts act as co-conspirators for chemotherapy resistance

(2010) Derek C. Radisky   CANCER BIOLOGY & THERAPY

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

3D microchannel co-culture: method and biological validation

(2010) Maret Bauer et al.   Integrative Biology

Imatinib mesylate inhibits the proliferation-stimulating effect of human lung cancer-associated stromal fibroblasts on lung cancer cells

(2010) Kinoshita   INTERNATIONAL JOURNAL OF ONCOLOGY

A microfluidic device for continuous cancer cell culture and passage with hydrodynamic forces

(2010) Liyu Liu et al.   LAB ON A CHIP

Microfluidic cell culture systems for drug research

(2010) Min-Hsien Wu et al.   LAB ON A CHIP

Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in EGFR-T790M Mutant Lung Cancer

(2009) T. Yamada et al.   CLINICAL CANCER RESEARCH

Lung Inflammation, Injury, and Proliferative Response after Repetitive Particulate Hexavalent Chromium Exposure

(2009) Laura M. Beaver et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Targeting the endoplasmic reticulum-stress response as an anticancer strategy

(2009) Sandra J.M. Healy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

(2009) Carlos P. Huang et al.   LAB ON A CHIP

Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer

(2009) M. L. Sos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro analysis of a hepatic device with intrinsic microvascular-based channels

(2008) Amedeo Carraro et al.   BIOMEDICAL MICRODEVICES

SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

(2008) B. Huang et al.   BLOOD

Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells

(2008) Yingyan Wang et al.   BMC CANCER

Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells

(2008) Masao Fujiwara et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Application of microfluidic gradient chip in the analysis of lung cancer chemotherapy resistance

(2008) Wang Siyan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A perfusable 3D cell-matrix tissue culture chamber for in situ evaluation of nanoparticle vehicle penetration and transport

(2007) Chee Ping Ng et al.   BIOTECHNOLOGY AND BIOENGINEERING