Sex Differences in Liver Toxicity—Do Female and Male Human Primary Hepatocytes React Differently to Toxicants In Vitro?

Editorial: Sex Matters in Preclinical Research

(2014) Stephen R. Hammes   MOLECULAR ENDOCRINOLOGY

Policy: NIH to balance sex in cell and animal studies

(2014) Janine A. Clayton et al.   NATURE

In pursuit of scientific excellence: sex matters

(2012) Virginia M. Miller   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sex Differences in Drug Disposition

(2011) Offie P. Soldin et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Reporting of sex as a variable in cardiovascular studies using cultured cells

(2011) K Taylor et al.   Biology of Sex Differences

Sex differences play a role in cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis induced by pressure overload and thapsigargin

(2010) Flori R. Sari et al.   CARDIOVASCULAR PATHOLOGY

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

(2010) Michael Ristow et al.   EXPERIMENTAL GERONTOLOGY

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Sex bias blights drug studies

(2010) Erika Check Hayden   NATURE

Males still dominate animal studies

(2010) Irving Zucker et al.   NATURE

Sex bias in neuroscience and biomedical research

(2010) Annaliese K. Beery et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Of Mice and Women: The Bias in Animal Models

(2010) C. Wald et al.   SCIENCE

Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

(2010) Li Liu et al.   TOXICOLOGY

An in vitro system for studying potential biological mechanisms of human sex differences in susceptibility to acute liver injury

(2010) Thomas J. Flynn et al.   TOXICOLOGY LETTERS

Gender differences in drug toxicity

(2010) Tamara J. Nicolson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Gender Issues in Transplantation

(2009) Marie Csete   ANESTHESIA AND ANALGESIA

Gender-dependent oxidative variations in liver of aged rats

(2009) Seval Aydın et al.   BIOGERONTOLOGY

Phenotypic characterization of idiosyncratic drug-induced liver injury: The influence of age and sex

(2009) M. Isabel Lucena et al.   HEPATOLOGY

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

(2009) Sebastian Schuck et al.   JOURNAL OF CELL BIOLOGY

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Gender differences in methionine accumulation and metabolism in freshly isolated mouse hepatocytes: Potential roles in toxicity

(2009) Joseph T. Dever et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tissue slices for the evaluation of metabolism-based toxicity with the example of diclofenac

(2008) Alison E.M. Vickers   CHEMICO-BIOLOGICAL INTERACTIONS

Women encounter ADRs more often than do men

(2008) Y. Zopf et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Chlorhexidine-induced apoptosis or necrosis in L929 fibroblasts: A role for endoplasmic reticulum stress

(2008) Gisele Faria et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY