Both Fasting and Glucose-Stimulated Proinsulin Levels Predict Hyperglycemia and Incident Type 2 Diabetes: A Population-Based Study of 9,396 Finnish Men

Disproportionately elevated proinsulinemia is observed at modestly elevated glucose levels within the normoglycemic range

(2014) Carlos Lorenzo et al.   ACTA DIABETOLOGICA

Estimated proinsulin processing activity of prohormone convertase (PC) 1/3 rather than PC2 is decreased in pancreatic ^|^beta;-cells of type 2 diabetic patients

(2014) Sachihiko Ozawa et al.   ENDOCRINE JOURNAL

Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic   cells

(2014) C. W. Liew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

(2012) Jeroen R Huyghe et al.   NATURE GENETICS

Proinsulin-to-C-peptide ratio versus proinsulin-to-insulin ratio in the prediction of incident diabetes: the Insulin Resistance Atherosclerosis Study (IRAS)

(2011) R. C. Loopstra-Masters et al.   DIABETOLOGIA

Proinsulin levels in patients with pancreatic diabetes are associated with functional changes in insulin secretion rather than pancreatic β-cell area

(2010) Thomas G K Breuer et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men

(2009) A. Stancakova et al.   DIABETES

 -Cell Dysfunction in Subjects With Impaired Glucose Tolerance and Early Type 2 Diabetes: Comparison of Surrogate Markers With First-Phase Insulin Secretion From an Intravenous Glucose Tolerance Test

(2008) A. Festa et al.   DIABETES