Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis

Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissue

(2012) F Mingozzi et al.   GENE THERAPY

scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints

(2012) R S Watson et al.   GENE THERAPY

Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins

(2011) Amit C Nathwani et al.   MOLECULAR THERAPY

Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?

(2010) Lisette Bevaart et al.   ARTHRITIS AND RHEUMATISM

Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors

(2010) Sylvie Boutin et al.   HUMAN GENE THERAPY

Safety of Liver Gene Transfer Following Peripheral Intravascular Delivery of Adeno-Associated Virus (AAV)-5 and AAV-6 in a Large Animal Model

(2010) Patricia Favaro et al.   HUMAN GENE THERAPY

Effect of Adeno-Associated Virus Serotype and Genomic Structure on Liver Transduction and Biodistribution in Mice of Both Genders

(2009) Astrid Pañeda et al.   HUMAN GENE THERAPY

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

(2009) Stephanie Lefèvre et al.   NATURE MEDICINE

Doxorubicin augments rAAV-2 transduction in rat neuronal cells

(2009) Ting Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy

(2008) G. P. Niemeyer et al.   BLOOD

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY