Letter
Medicine, General & Internal
Krishna Pundi, Kensey L. Gosch, Alexander C. Perino, Philip G. Jones, Nihar R. Desai, Thomas M. Maddox, Mintu Turakhia
Summary: This cohort study compared the incidence of hypertension among nonhypertensive patients with atrial fibrillation using JNC 8 and ACC/AHA thresholds.
Article
Medicine, General & Internal
Thomas Jensen, Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Morten Wurtz, Jens Cosedis Nielsen, Lisette Okkels Jensen, Morten Madsen, Troels Thim, Steen Dalby Kristensen, Gregory Y. H. Lip, Michael Maeng
Summary: The CHA(2)DS(2)-VASc score implementation in the 2010 European guidelines on AF was associated with increased utilization of oral anticoagulation and triple therapy among AF patients undergoing PCI. These changes were linked to a gradual decline in the risk of major adverse cardiac events, while the risk of hospitalized bleeding remained stable.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Cardiac & Cardiovascular Systems
Yuzhong Wu, Zengshuo Xie, Weihao Liang, Ruicong Xue, Zexuan Wu, Dexi Wu, Jiangui He, Wengen Zhu, Chen Liu
Summary: This study examined the utility of CHADS2, R2CHADS2, and CHA2DS2-VASc scores in predicting incident AF in HFpEF patients, revealing their ability to predict AF risk with moderate accuracy.
Article
Medicine, General & Internal
Inwu Yu, Tae-Jin Song, Bum Joon Kim, Sung Hyuk Heo, Jin-Man Jung, Kyung-Mi Oh, Chi Kyung Kim, Sungwook Yu, Kwang Yeol Park, Jeong-Min Kim, Jong-Ho Park, Jay Chol Choi, Man-Seok Park, Joon-Tae Kim, Yang-Ha Hwang, Jong-Won Chung, Oh Young Bang, Geong-Moon Kim, Yong-Jae Kim, Seonwoo Kim, Sook Young Woo, Hyun Cho, Woo-Keun Seo
Summary: The performance of scoring systems for risk stratification in patients with atrial fibrillation (AF) was not well validated in patients with stroke. Among stroke patients with AF, CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen stroke risk scores were not associated with recurrent ischemic stroke and any stroke, but were correlated with death and major adverse cerebrovascular and cardiovascular events (MACEs), particularly in the group treated with oral anticoagulants (OACs). A new risk stratification scheme specific to secondary stroke prevention in the AF population is needed.
Article
Cardiac & Cardiovascular Systems
Joshua Rutland, Karam Ayoub, Farshid Etaee, Gbolahan Ogunbayo, Yousef Darrat, Meera Marji, Ahmad Masri, Claude S. Elayi
Summary: The study showed that the CHA2DS2-VASc risk score can identify patients without prior history of atrial fibrillation/flutter who are at risk of hospital readmissions with atrial arrhythmias or acute cerebrovascular accident within 6 months of hospitalization.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, Research & Experimental
Miaomiao Cao, Huihui Guo, Xiao Zhao, Xiyang Li, Chaofeng Sun
Summary: This study investigates the risk factors of left atrial thrombus/spontaneous echo contrast in patients with nonvalvular atrial fibrillation. Non-paroxysmal AF and increased left atrial diameter are identified as independent risk factors beyond the traditional risk scores and can be used to improve risk stratification.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2022)
Review
Cardiac & Cardiovascular Systems
Kathryn D. Tiver, Jing Quah, Anandaroop Lahiri, Anand N. Ganesan, Andrew D. McGavigan
Summary: Atrial fibrillation (AF) burden may exhibit a biological gradient with stroke risk, suggesting that different levels of AF burden could impact the risk of stroke in patients. Combining AF burden assessment with clinical risk scoring can help refine the assessment of stroke risk in AF patients.
Article
Medicine, General & Internal
W. S. Hu, C. L. Lin, C. Y. Hsu
Summary: This study found that acupuncture has a protective effect on reducing the risk of atrial fibrillation (AF), with a more obvious effect observed in patients with fewer comorbidities. The results show decreased incidence of AF in different groups based on CHA(2)DS(2)-VASc scores, supporting the potential benefits of acupuncture in AF risk reduction.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Mariam Anjum, Inger Ariansen, Vidar Hjellvik, Randi Selmer, Lars J. Kjerpeseth, Eva Skovlund, Marius Myrstad, Hanne Ellekjaer, Ingrid E. Christophersen, Arnljot Tveit, Trygve Berge
Summary: In patients with atrial fibrillation (AF) at intermediate risk of stroke, oral anticoagulant use was associated with overall favorable clinical outcomes. Non-anticoagulated AF patients had a higher risk of ischemic stroke compared to individuals without AF but with the same risk profile.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Hyo-Jeong Ahn, So-Ryoung Lee, Eue-Keun Choi, Seung-Woo Lee, Kyung-Do Han, Soonil Kwon, Seil Oh, Gregory Y. H. Lip
Summary: This study investigated the association between metabolic syndrome (MetS) and the risk of ischemic stroke in atrial fibrillation (AF) patients without indication for oral anticoagulants. The findings showed that MetS was associated with an increased risk of ischemic stroke in this patient population.
Review
Cardiac & Cardiovascular Systems
Tariq Jamal Siddiqi, Muhammad Shariq Usman, Izza Shahid, Jawad Ahmed, Safi U. Khan, Lina Ya'qoub, Charanjit S. Rihal, Mohamad Alkhouli
Summary: This meta-analysis suggests that the discrimination power of the CHA(2)DS(2)-VASc score in predicting ischaemic stroke is modest, and is similar in the presence or absence of NVAF. More accurate stroke prediction models are thus needed for the NVAF population.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Tingting Guo, Ziwei Xi, Hong Qiu, Yong Wang, Jianfeng Zheng, Kefei Dou, Bo Xu, Shubin Qiao, Weixian Yang, Runlin Gao
Summary: The GRACE and CHA2DS2-VASc risk scores were evaluated for risk prediction in atrial fibrillation patients undergoing PCI, with the study finding that high GRACE score, but not CHA2DS2-VASc score, was associated with an increased risk of major adverse cardiac events. Additionally, both scores demonstrated good ability in predicting all-cause mortality.
ANNALS OF MEDICINE
(2021)
Article
Clinical Neurology
Ki-Woong Nam, Chi Kyung Kim, Sungwook Yu, Jong-Won Chung, Oh Young Bang, Gyeong-Moon Kim, Jin-Man Jung, Tae-Jin Song, Yong-Jae Kim, Bum Joon Kim, Sung Hyuk Heo, Kwang-Yeol Park, Jeong-Min Kim, Jong-Ho Park, Jay Chol Choi, Man-Seok Park, Joon-Tae Kim, Kang-Ho Choi, Yang Ha Hwang, Kyungmi Oh, Woo-Keun Seo
Summary: The study revealed a significant association between high CHA(2)DS(2)-VASc score and early neurological deterioration in ischemic stroke patients with atrial fibrillation, particularly in those with intracranial atherosclerosis(ICAS).
CEREBROVASCULAR DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Guangyu Wang, Guangyu Li, Feng Hu, Minhua Zang, Jun Pu
Summary: The study aimed to explore the feasibility of using LA diameter (LAD) combined with CHA(2)DS(2)-VASc score as a new assessment tool for predicting a decrease in left atrial appendage flow velocity (LAAFV) in patients with non-valvular atrial fibrillation (NVAF). The results showed that patients with larger LAD and higher CHA(2)DS(2)-VASc scores had a greater decrease in LAAFV. Multivariate linear and logistic regression models further demonstrated that LAD and CHA(2)DS(2)-VASc score could independently predict a decrease in LAAFV.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Medicine, General & Internal
Bo-Yuan Wang, Fei-Yi Lin, Min-Sho Ku, Yu-Hsun Wang, Kun-Yu Lee, Sai-Wai Ho
Summary: Recent studies have shown that the CHA2DS2-VASc score can predict the risk of major adverse cardiovascular events in pneumonia patients, with higher scores indicating a greater likelihood of MACE occurrence. The score demonstrated good predictive performance for MACE in both the atrial fibrillation and non-atrial fibrillation groups.
JOURNAL OF CLINICAL MEDICINE
(2021)