New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease

Ubiquitination of α-synuclein and autophagy in Parkinson's disease

(2014) Simone Engelender   Autophagy

In vitro aggregation assays for the characterization of α-synuclein prion-like properties

(2014) Joanna Narkiewicz et al.   Prion

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

(2013) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperstimulation of macropinocytosis leads to lysosomal dysfunction during exposure to methamphetamine in SH-SY5Y cells

(2012) Akina Nara et al.   BRAIN RESEARCH

Age-related Changes in Rat Myocardium Involve Altered Capacities of Glycosaminoglycans to Potentiate Growth Factor Functions and Heparan Sulfate-altered Sulfation

(2012) Minh Bao Huynh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Self-evolving oxidative stress with identifiable pre- and postmitochondrial phases in PC12 cells

(2012) Ganlin Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship

(2012) Maria Xilouri et al.   MOLECULAR NEUROBIOLOGY

Glycosaminoglycans, Protein Aggregation and Neurodegeneration

(2011) Dulce Papy-Garcia et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Distinct Roles In Vivo for the Ubiquitin-Proteasome System and the Autophagy-Lysosomal Pathway in the Degradation of  -Synuclein

(2011) D. Ebrahimi-Fakhari et al.   JOURNAL OF NEUROSCIENCE

Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism

(2011) Sowmya V Yelamanchili et al.   Molecular Neurodegeneration

Genetic and pathological links between Parkinson's disease and the lysosomal disorder Sanfilippo syndrome

(2011) Sophie E. Winder-Rhodes et al.   MOVEMENT DISORDERS

Distinct Region-Specific  -Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration

(2010) E. Tsika et al.   JOURNAL OF NEUROSCIENCE

Pathogenic Lysosomal Depletion in Parkinson's Disease

(2010) B. Dehay et al.   JOURNAL OF NEUROSCIENCE

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic

(2009) X-L Yue et al.   CELL DEATH AND DIFFERENTIATION

Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

(2009) Yaping Chu et al.   NEUROBIOLOGY OF DISEASE

Pathogenesis of Parkinson's disease: emerging role of molecular chaperones

(2009) Rina Bandopadhyay et al.   TRENDS IN MOLECULAR MEDICINE

Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo

(2009) Valerie Cullen et al.   Molecular Brain

Cathepsin D Is the Main Lysosomal Enzyme Involved in the Degradation of α-Synuclein and Generation of Its Carboxy-Terminally Truncated Species†

(2008) Daniel Sevlever et al.   BIOCHEMISTRY

Chondroitin-4-sulfation negatively regulates axonal guidance and growth

(2008) H. Wang et al.   JOURNAL OF CELL SCIENCE

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

(2008) Claire Henchcliffe et al.   Nature clinical practice. Neurology

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

(2008) Liyan Qiao et al.   Molecular Brain