Article
Agriculture, Multidisciplinary
Ling Ying-hui, Zheng Qi, Jing Jing, Sui Meng-hua, Zhu Lu, Li Yun-sheng, Zhang Yun-hai, Liu Ya, Fang Fu-gui, Zhang Xiao-rong
Summary: By analyzing the transcriptome of goat skeletal muscle at different growth stages, this study uncovered the functions and metabolic pathways of different modules during muscle development. The results revealed that DEGs at different stages play various roles in regulating muscle proliferation, structure, and fatty acid processes, providing a theoretical basis for understanding the involvement of mRNA in skeletal muscle development.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2021)
Article
Genetics & Heredity
Xing Wan, Jia-Nan Jing, Dong-Feng Wang, Feng-Hua Lv
Summary: This study used whole-genome resequencing data to investigate goat breeds with outstanding traits and identified 210-531 genomic regions related to six economic phenotypic traits. The study discovered both previously reported genes and novel genes associated with these traits. It provides new genetic markers for genetic improvement in goats and insights into the genetic mechanisms of complex traits.
FRONTIERS IN GENETICS
(2023)
Article
Veterinary Sciences
Le Zhao, Haili Yang, Xingchun Li, Yumei Zhou, Taolu Liu, Yongju Zhao
Summary: This study evaluated candidate reference genes for the early whiting mechanism of goat brown adipose tissue (BAT) and identified the most stable reference genes. These findings contribute to further understanding the molecular mechanisms underlying BAT whiting in goats and provide important reference genes for research in this field.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Sadegh Taheri, Naghmeh Saedi, Saeed Zerehdaran, Ali Javadmanesh
Summary: Identification of selection signatures in domestic and wild goats from Iran reveals the candidate genes and traits associated with domestication, including milk production, fleece trait, mammary epithelial cells, reproduction, and immune system. Using RSB, iHS, and XP-EHH statistics, this study identified a total of 675 selection signatures in wild goats and 441 selection signatures in domestic goats using the iHS method. The RSB and XP-EHH methods identified approximately 370 selection signatures in wild goats and 447 selection signatures in domestic goats.
ANIMAL SCIENCE JOURNAL
(2023)
Article
Agriculture, Dairy & Animal Science
Yaping Song, Dawei Wei, Sayed Haidar Abbas Raza, Yiang Zhao, Chao Jiang, Xiaoyu Song, Hao Wu, Xingping Wang, Zhuoma Luoreng, Yun Ma
Summary: Intramuscular fat (IMF) is closely related to the meat quality of livestock and poultry. Cell co-culture, a new technique in vitro, has been gradually applied to the research of IMF formation to simulate the changes of microenvironment in vivo. This paper reviews the generation of IMF, summarizes existing co-culture methods and systems, and discusses the advantages, disadvantages, and challenges faced in establishing the system. The current research status of IMF formation based on co-culture technology for humans and animals is also emphasized.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Laure Denoyelle, Estelle Talouarn, Philippe Bardou, Licia Colli, Adriana Alberti, Coralie Danchin, Marcello Del Corvo, Stefan Engelen, Celine Orvain, Isabelle Palhiere, Rachel Rupp, Julien Sarry, Mazdak Salavati, Marcel Amills, Emily Clark, Paola Crepaldi, Thomas Faraut, Clet Wandui Masiga, Francois Pompanon, Benjamin D. Rosen, Alessandra Stella, Curtis P. Van Tassell, Gwenola Tosser-Klopp
Summary: The VarGoats project aimed to understand the genetic diversity of domestic goats through an international 1000-genome resequencing program. The dataset collected included sequenced goats from various regions and identified numerous genetic variations. The study found that goat populations from different continents tend to cluster into independent groups, reflecting their diverse genetic backgrounds and geographic origins.
GENETICS SELECTION EVOLUTION
(2021)
Article
Multidisciplinary Sciences
Martin A. Belzunce, Johann Henckel, Anna Di Laura, Alister Hart
Summary: This study aimed to investigate the association between gluteus maximus (GMAX) fat infiltration and different levels of physical activity. The results indicated that hip pain, low physical activity, female gender, and high BMI were significant predictors of increased GMAX fat infiltration.
SCIENTIFIC REPORTS
(2021)
Article
Agriculture, Dairy & Animal Science
Huimin Kang, Di Zhao, Hai Xiang, Jing Li, Guiping Zhao, Hua Li
Summary: We conducted association analyses based on breast muscle transcriptomic data to identify candidate genes for breast muscle weight and IMF contents in Tiannong partridge chickens. The study evaluated different statistical models and detected several candidate genes associated with these economic traits, which are involved in muscle development, contraction, and lipid metabolism. This research provides valuable insights for genetic improvement programs in broiler chickens.
GENETICS SELECTION EVOLUTION
(2021)
Article
Health Care Sciences & Services
Simon Kwoon-Ho Chow, Marloes van Mourik, Vivian Wing-Yin Hung, Ning Zhang, Michelle Meng-Chen Li, Ronald Man-Yeung Wong, Kwok-Sui Leung, Wing-Hoi Cheung
Summary: This study aimed to develop a method for detecting and analyzing intramuscular fat infiltration in skeletal muscle using clinical HR-pQCT images for the evaluation of muscle during the aging process. The method was validated using animal and clinical experimentation. The results showed that the proposed method was effective in both animal models and human subjects and correlated with age and muscle function.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Biotechnology & Applied Microbiology
Siyuan Zhan, Yanan Xue, Liu Yang, Dandan Li, Haodong Dai, Tao Zhong, Linjie Wang, Dinghui Dai, Li Li, Hongping Zhang
Summary: In this study, 466 antisense lncRNAs (ASlncRNAs) were identified in the longissimus dorsi muscle of goats. These ASlncRNAs were found to be potentially involved in muscle development by negatively regulating the expression of target genes and producing miRNA precursors. This research provides a catalogue of goat muscle-related ASlncRNAs and contributes to a better understanding of the roles of ASlncRNAs in muscle development.
Article
Agriculture, Dairy & Animal Science
Chunlin Xie, Junyong Teng, Xinkai Wang, Baoyang Xu, Yaorong Niu, Libao Ma, Xianghua Yan
Summary: The gut microbiome has been found to influence lipid deposition in both pig and mouse muscle, with certain microbiota selectively enhancing fat deposition and altering meat quality. Fecal microbiota transplantation experiments revealed core species that regulate lipid deposition, and further analysis in mice confirmed the relationship between microbiota and intramuscular fat content. These findings highlight the importance of the gut microbiota in regulating lipid deposition in both pigs and mice.
Article
Multidisciplinary Sciences
Maya Hioki, Nana Kanehira, Teruhiko Koike, Akira Saito, Kiyoshi Shimaoka, Hisataka Sakakibara, Yoshiharu Oshida, Hiroshi Akima
Summary: This study found that intramuscular adipose tissue is negatively correlated with adiponectin levels in normal-weight older adults, independent of waist circumference. Additionally, the dynamics of adiponectin differ from other circulating biochemical parameters in older men and women.
Article
Agriculture, Dairy & Animal Science
Le Zhao, Yongheng Yang, Haili Yang, Nanjian Luo, Xingchun Li, Jikang Zheng, Songjian Yang, Yongju Zhao
Summary: This study systematically collected goat uterine tissue at different stages of pregnancy and used RNA-seq to screen for genes related to embryo implantation. The differentially expressed genes and enriched signaling pathways provide valuable references for exploring the molecular mechanisms of goat embryo implantation.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Veterinary Sciences
Minghui Wang, Hongchao Jiao, Jingpeng Zhao, Hai Lin, Xiaojuan Wang
Summary: The study investigates the role of FATP1 in the regulation of fatty acid uptake and deposition in stressed broiler chickens. The results suggest that FATP1 regulation by glucocorticoids is influenced by the type of fatty acid substrate, with saturated fatty acids favoring fat uptake and deposition. Glucocorticoids may affect the ADPNR-PPAR alpha-FATP1 pathway and regulate the uptake of saturated fatty acids into myoblasts.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Cell Biology
Weihua Tian, Zhang Wang, Dandan Wang, Yihao Zhi, Jiajia Dong, Ruirui Jiang, Ruili Han, Zhuanjian Li, Xiangtao Kang, Hong Li, Xiaojun Liu
Summary: The study found that Chinese indigenous Lushi blue-shelled-egg chickens have higher IMF content but lower muscle fiber diameter in the breast muscle compared to commercial Arbor Acres broilers. In both AA and LS chickens, chromatin intra-interactions were more prevalent than inter-interactions, with a focus on small and gene-rich chromosomes. AA had more A type compartments compared to LS chickens, and exhibited more A to B compartment switching.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)