In-Silico Analysis of Inflammatory Bowel Disease (IBD) GWAS Loci to Novel Connections

Coeliac disease-associated polymorphisms influence thymic gene expression

(2014) S S Amundsen et al.   GENES AND IMMUNITY

SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease

(2014) Sharyle A. Fowler et al.   Journal of Crohns & Colitis

A promoter-level mammalian expression atlas

(2014)   NATURE

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk

(2014) Ben Zhang et al.   NATURE GENETICS

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Heritability and genomics of gene expression in peripheral blood

(2014) Fred A Wright et al.   NATURE GENETICS

Functional annotation of noncoding sequence variants

(2014) Graham R S Ritchie et al.   NATURE METHODS

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease

(2014) S Bank et al.   PHARMACOGENOMICS JOURNAL

Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings

(2014) Samantha L. Rosenthal et al.   PLoS One

The SNP rs1883832 in CD40 Gene and Risk of Atherosclerosis in Chinese Population: A Meta-Analysis

(2014) Yan Yun et al.   PLoS One

Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

(2014) John N. Hutchinson et al.   PLoS One

Explaining additional genetic variation in complex traits

(2014) Matthew R. Robinson et al.   TRENDS IN GENETICS

Functional interpretation of non-coding sequence variation: Concepts and challenges

(2013) Dirk S. Paul et al.   BIOESSAYS

Expression Quantitative Trait Loci Analysis Identifies Associations Between Genotype and Gene Expression in Human Intestine

(2013) Boyko Kabakchiev et al.   GASTROENTEROLOGY

Many Inflammatory Bowel Disease Risk Loci Include Regions That Regulate Gene Expression in Immune Cells and the Intestinal Epithelium

(2013) Michal Mokry et al.   GASTROENTEROLOGY

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

Geographical variability and environmental risk factors in inflammatory bowel disease

(2013) Siew C Ng et al.   GUT

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

(2013) M Zaeem Cader et al.   GUT

The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine

(2013) Peter D. Stenson et al.   HUMAN GENETICS

The Burden of Comedication Among Patients with Inflammatory Bowel Disease

(2013) Jessie P. Buckley et al.   INFLAMMATORY BOWEL DISEASES

Risk factors of work disability in patients with inflammatory bowel disease — A Dutch nationwide web-based survey

(2013) Mirthe E. van der Valk et al.   Journal of Crohns & Colitis

National estimates of the burden of inflammatory bowel disease among racial and ethnic groups in the United States

(2013) Geoffrey C. Nguyen et al.   Journal of Crohns & Colitis

Genome-wide significant association ofANKRD55rs6859219 and multiple sclerosis risk

(2013) Christina M Lill et al.   JOURNAL OF MEDICAL GENETICS

New loci associated with chronic hepatitis B virus infection in Han Chinese

(2013) Zhibin Hu et al.   NATURE GENETICS

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

(2013) Adrian Cortes et al.   NATURE GENETICS

A large-scale screen for coding variants predisposing to psoriasis

(2013) Huayang Tang et al.   NATURE GENETICS

Genetic insights into common pathways and complex relationships among immune-mediated diseases

(2013) Miles Parkes et al.   NATURE REVIEWS GENETICS

GeneMANIA Prediction Server 2013 Update

(2013) Khalid Zuberi et al.   NUCLEIC ACIDS RESEARCH

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Ensembl 2014

(2013) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

Association of SNPs of CD40 Gene with Multiple Sclerosis in Russians

(2013) Ekaterina Alekseevna Sokolova et al.   PLoS One

Genomic Medicine: A Decade of Successes, Challenges, and Opportunities

(2013) J. J. McCarthy et al.   Science Translational Medicine

The challenges of stratifying patients for trials in inflammatory bowel disease

(2013) Paolo Biancheri et al.   TRENDS IN IMMUNOLOGY

Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

(2012) David Ellinghaus et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of celiac disease genes with inflammatory bowel disease in Finnish and Swedish patients

(2012) A S Parmar et al.   GENES AND IMMUNITY

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study

(2012) Mirthe Emilie van der Valk et al.   GUT

Inflammatory bowel disease in Asia: A systematic review

(2012) Lani Prideaux et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Interpreting noncoding genetic variation in complex traits and human disease

(2012) Lucas D Ward et al.   NATURE BIOTECHNOLOGY

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

A travel guide to Cytoscape plugins

(2012) Rintaro Saito et al.   NATURE METHODS

Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions

(2012) L. D. Ward et al.   SCIENCE

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data

(2011) Gregory M. Cooper et al.   NATURE REVIEWS GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease

(2010) Karin Fransen et al.   HUMAN MOLECULAR GENETICS

genenames.org: the HGNC resources in 2011

(2010) R. L. Seal et al.   NUCLEIC ACIDS RESEARCH

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

FunctionalFEN1polymorphisms are associated with DNA damage levels and lung cancer risk

(2009) Ming Yang et al.   HUMAN MUTATION

Genome-wide association studies: potential next steps on a genetic journey

(2008) M. I. McCarthy et al.   HUMAN MOLECULAR GENETICS