A Novel Mouse Model for Stable Engraftment of a Human Immune System and Human Hepatocytes

Lymphocytes Support Oval Cell-Dependent Liver Regeneration

(2014) H. Strick-Marchand et al.   JOURNAL OF IMMUNOLOGY

FLT3-Ligand Treatment of Humanized Mice Results in the Generation of Large Numbers of CD141+ and CD1c+ Dendritic Cells In Vivo

(2014) Y. Ding et al.   JOURNAL OF IMMUNOLOGY

Extensive double humanization of both liver and hematopoiesis in FRGN mice

(2014) Elizabeth M. Wilson et al.   Stem Cell Research

Human Hepatocytes and Hematolymphoid Dual Reconstitution in Treosulfan-Conditioned uPA-NOG Mice

(2013) Tanuja L. Gutti et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine

(2013) Anthony Rongvaux et al.   Annual Review of Immunology

Studies of Lymphocyte Reconstitution in a Humanized Mouse Model Reveal a Requirement of T Cells for Human B Cell Maturation

(2013) J. Lang et al.   JOURNAL OF IMMUNOLOGY

Characterization of Human Antiviral Adaptive Immune Responses during Hepatotropic Virus Infection in HLA-Transgenic Human Immune System Mice

(2013) E. Billerbeck et al.   JOURNAL OF IMMUNOLOGY

Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies

(2013) John R. Foster et al.   XENOBIOTICA

Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease

(2012) Jens Bukh   GASTROENTEROLOGY

Development of Mature and Functional Human Myeloid Subsets in Hematopoietic Stem Cell-Engrafted NOD/SCID/IL2r KO Mice

(2012) S. Tanaka et al.   JOURNAL OF IMMUNOLOGY

GM-CSF and IL-4 Stimulate Antibody Responses in Humanized Mice by Promoting T, B, and Dendritic Cell Maturation

(2012) Q. Chen et al.   JOURNAL OF IMMUNOLOGY

Experimental models and therapeutic approaches for HBV

(2012) Maura Dandri et al.   Seminars in Immunopathology

A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease

(2011) Michael L. Washburn et al.   GASTROENTEROLOGY

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

(2011) Kosuke Yusa et al.   NATURE

IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo

(2011) N. D. Huntington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

(2011) Nicolas Legrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models in the study of hepatitis C virus-associated liver pathologies

(2011) Hervé Lerat et al.   Expert Review of Gastroenterology & Hepatology

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

(2010) Karl-Dimiter Bissig et al.   JOURNAL OF CLINICAL INVESTIGATION

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice

(2010) Thomas Vanwolleghem et al.   JOURNAL OF HEPATOLOGY

Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice

(2009) Dhivya Haridass et al.   AMERICAN JOURNAL OF PATHOLOGY

Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook

(2009) Nicolas Legrand et al.   Cell Host & Microbe

The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV

(2008) P MEULEMAN et al.   ANTIVIRAL RESEARCH

Which in vitro models could be best used to study hepatocyte polarity?

(2008) Catherine Decaens et al.   BIOLOGY OF THE CELL

Cell therapy for the diseased liver: from stem cell biology to novel models for hepatotropic human pathogens

(2008) N. Brezillon et al.   Disease Models & Mechanisms

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE