Isoform Switch of Pyruvate Kinase M1 Indeed Occurs but Not to Pyruvate Kinase M2 in Human Tumorigenesis

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

(2015) Katharina Bluemlein et al.   Oncotarget

Identification of reference genes for qRT-PCR in human lung squamous-cell carcinoma by RNA-Seq

(2014) Cheng Zhan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

A review of the current epidemiology and treatment options for prostate cancer

(2014) Daniel M. Saman et al.   DM DISEASE-A-MONTH

Human Papillomavirus 16 E6 Contributes HIF-1α Induced Warburg Effect by Attenuating the VHL-HIF-1α Interaction

(2014) Yi Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prognostic significance of serum lactate dehydrogenase level in osteosarcoma: a meta-analysis

(2014) Jian Chen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma

(2014) Ye Song et al.   Molecular Cancer

Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma

(2014) Hala Girgis et al.   Molecular Cancer

Mass-spectrometry-based draft of the human proteome

(2014) Mathias Wilhelm et al.   NATURE

LDH5 overexpression is associated with poor survival in patients with solid tumors: a meta-analysis

(2014) YanHong Yao et al.   TUMOR BIOLOGY

Nuclear localization of aldolase A correlates with cell proliferation

(2013) Piotr Mamczur et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Hexokinase II in breast carcinoma: A potent prognostic factor associated with hypoxia-inducible factor-1α and Ki-67

(2013) Akiko Sato-Tadano et al.   CANCER SCIENCE

PKM2 and ACVR 1C are prognostic markers for poor prognosis of gallbladder cancer

(2013) J. Li et al.   Clinical & Translational Oncology

Lactate Dehydrogenase B: A Metabolic Marker of Response to Neoadjuvant Chemotherapy in Breast Cancer

(2013) J. B. Dennison et al.   CLINICAL CANCER RESEARCH

Quantitative Proteomics Profiling of Primary Lung Adenocarcinoma Tumors Reveals Functional Perturbations in Tumor Metabolism

(2013) Maria Pernemalm et al.   JOURNAL OF PROTEOME RESEARCH

High expression of glycolytic and pigment proteins is associated with worse clinical outcome in stage III melanoma

(2013) Johan Falkenius et al.   MELANOMA RESEARCH

Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients

(2013) Roberto Puzone et al.   Molecular Cancer

Cetuximab Reverses the Warburg Effect by Inhibiting HIF-1-Regulated LDH-A

(2013) H. Lu et al.   MOLECULAR CANCER THERAPEUTICS

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

(2013) Fan Yang et al.   MOLECULAR CELL

Nuclear PKM2 expression predicts poor prognosis in patients with esophageal squamous cell carcinoma

(2013) Xuelin Zhang et al.   PATHOLOGY RESEARCH AND PRACTICE

The Expression of Glyceraldehyde-3-Phosphate Dehydrogenase Associated Cell Cycle (GACC) Genes Correlates with Cancer Stage and Poor Survival in Patients with Solid Tumors

(2013) Dunrui Wang et al.   PLoS One

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism

(2013) H.-J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hexokinase 2 overexpression promotes the proliferation and survival of laryngeal squamous cell carcinoma

(2013) Jian Chen et al.   TUMOR BIOLOGY

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

(2012) Ilaria Dando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-Bromopyruvate Propyl Ester

(2012) Zhenjie Tang et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Proteomic identification of PKM2 and HSPA5 as potential biomarkers for predicting high-risk endometrial carcinoma

(2012) Yincheng Teng et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase

(2012) Xueliang Gao et al.   MOLECULAR CELL

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Overexpression of the M2 isoform of pyruvate kinase is an adverse prognostic factor for signet ring cell gastric cancer

(2012) Jae Yun Lim   WORLD JOURNAL OF GASTROENTEROLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

The M2-type isoenzyme of pyruvate kinase phosphorylates prothymosin α in proliferating lymphocytes

(2010) Cristina Díaz-Jullien et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells

(2010) Sybille Mazurek   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply

(2009) Gilles A. Spoden et al.   EXPERIMENTAL CELL RESEARCH

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS