WW Domains of the Yes-Kinase-Associated-Protein (YAP) Transcriptional Regulator Behave as Independent Units with Different Binding Preferences for PPxY Motif-Containing Ligands

YAP regulates neuronal differentiation through Sonic hedgehog signaling pathway

(2012) Yi-Ting Lin et al.   EXPERIMENTAL CELL RESEARCH

Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene

(2012) Christian J. Gaffney et al.   GENE

MM-ISMSA: An Ultrafast and Accurate Scoring Function for Protein–Protein Docking

(2012) Javier Klett et al.   Journal of Chemical Theory and Computation

Biophysical Basis of the Binding of WWOX Tumor Suppressor to WBP1 and WBP2 Adaptors

(2012) Caleb B. McDonald et al.   JOURNAL OF MOLECULAR BIOLOGY

WW Domains in the Heart of Smad Regulation

(2012) Marius Sudol   STRUCTURE

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways

(2012) Eric Aragón et al.   STRUCTURE

Interfacial water molecules in SH3 interactions: a revised paradigm for polyproline recognition

(2011) Jose M. Martin-Garcia et al.   BIOCHEMICAL JOURNAL

Structural Features and Ligand Binding Properties of Tandem WW Domains from YAP and TAZ, Nuclear Effectors of the Hippo Pathway

(2011) Claire Webb et al.   BIOCHEMISTRY

The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesis

(2011) Hsi-Ju Chen et al.   DEVELOPMENTAL BIOLOGY

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

(2011) E. Aragon et al.   GENES & DEVELOPMENT

Multivalent Binding of Formin-binding Protein 21 (FBP21)-Tandem-WW Domains Fosters Protein Recognition in the Pre-spliceosome

(2011) Stefan Klippel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Opposing roles of angiomotin-like-1 and zona occludens-2 on pro-apoptotic function of YAP

(2011) T Oka et al.   ONCOGENE

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Computational Design and Experimental Testing of the Fastest-Folding β-Sheet Protein

(2010) Stefano Piana et al.   JOURNAL OF MOLECULAR BIOLOGY

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

(2010) P. A. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WW: An isolated three-stranded antiparallel β-sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state

(2010) Edward K. Koepf et al.   PROTEIN SCIENCE

Atomic-Level Characterization of the Structural Dynamics of Proteins

(2010) D. E. Shaw et al.   SCIENCE

Modularity in the Hippo signaling pathway

(2010) Marius Sudol et al.   TRENDS IN BIOCHEMICAL SCIENCES

Thermodynamic Characterization of the Folding Equilibrium of the Human Nedd4-WW4 Domain: At the Frontiers of Cooperative Folding

(2009) Eva S. Cobos et al.   BIOCHEMISTRY

A Thermodynamic Approach to the Affinity Optimization of Drug Candidates

(2009) Ernesto Freire   Chemical Biology & Drug Design

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

(2009) A. Fernandez-L et al.   GENES & DEVELOPMENT

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structural characterisation of PinA WW domain and a comparison with other Group IV WW domains, Pin1 and Ess1

(2008) Chai Ann Ng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Do enthalpy and entropy distinguish first in class from best in class?

(2008) E FREIRE   DRUG DISCOVERY TODAY

Mst2 and Lats Kinases Regulate Apoptotic Function of Yes Kinase-associated Protein (YAP)

(2008) Tsutomu Oka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hippo Pathway Promotes Notch Signaling in Regulation of Cell Differentiation, Proliferation, and Oocyte Polarity

(2008) Jianzhong Yu et al.   PLoS One